Association of Xmn I Polymorphism and Hemoglobin E Haplotypes on Postnatal Gamma Globin Gene Expression in Homozygous Hemoglobin E

Table 2

Comparison of alkaline F % (±SD) in homozygous HbE with different Xmn I alleles.

Xmn I; genotype	Male		Female		𝑃 value
	𝑁	Alkaline F (%)	𝑁	Alkaline F (%)
+/+	18	2.34 ± 1.24	24	3.38 ± 0.26	<0.05
+/−	10	1.93 ± 0.27	20	2.83 ± 2.5	<0.05
−/−	2	1, 3.5	0	NA	NA

*significantly difference (𝑃<0.05) between male and female subjects with similar XmnI genotypes. NA: not available.