Research Article

Approach to Management of Thrombotic Thrombocytopenic Purpura at University of Cincinnati

Table 1

Characteristics of patients in PE and PE + R/C arm.

VariableCategoryAll ( )PE (13)PE + R/C (9) value

Age41.546380.3771
GenderFemale19 (86.4%)10 (76.9)9 (100)0.2403
RaceAfrican-American16 (72.7%)8 (61.5%)8 (88.9%)0.3330
New/RelapsedRelapsed5 (22.7%)1 (7.7%)4 (44.4%)0.1159
PregnancyYes3 (13.6%)3 (23.1%)0 (0%)0.2403
SchistocytesPresent21 (95.5%)12 (92.3%)9 (100%)1.000
ProteinuriaYes9 (40.9%)4 (30.8%)5 (55.6%)0.3842
Died6 (27.3%)6 (46.2%)0 (0%)0.0461
Platelets ( 1000)15.5 (0.03, 60)21 (4, 60)8 (0.03, 27)0.0839
WBC10.4 (3.7, 16.4)10.8 (4.1, 10.8)8.9 (3.7, 16.4)0.6706
Hb8.5 (4.4, 10.7)8.8 (6.4, 10.2)7.4 (4.4, 10.7)0.3602
Reticulocytes4.9 (3.0, 12.3)4.0 (3.0, 12.3)7.1 (4.2, 11.5)0.3624
Creatinine1.0 (0.04, 9.8)1.4 (0.4, 9.8)1.0 (0.5, 1.9)0.2018
LDH827.5 (225, 2437)1000 (225, 2302)698 (226, 2437)0.7283
Duration of PE252 (53, 2624)284 (53, 2337)220 (69, 2624)0.7418
Time between 1st PE and 1st Ritual69 (0, 2375)