Sonoclot Signature Analysis in Patients with Liver Disease and Its Correlation with Conventional Coagulation Studies

Table 4

Correlation obtained between sonoclot parameters and conventional coagulation variables in patients with liver disease.

Conventional tests		PT-INR	APTT	Fibrinogen	D-dimer	Platelet count
Sonoclot parameters	𝑃 value (𝑟: correlation coefficient)
	SonACT	<0.008 (𝑟=0.36)	<0.0015 (𝑟=0.43)	<0.037 (𝑟=−0.29)	0.39 (𝑟=0.12)	<0.01 (𝑟=−0.34)
	CR	<0.0025 (𝑟=−0.41)	<0.0025 (𝑟=−0.41)	<0.004 (𝑟=0.39)	0.96 (𝑟=−0.005)	<0.03 (𝑟=0.3)
	PF	0.07 (𝑟=−0.25)	0.2 (𝑟=−0.16)	<0.001 (𝑟=0.44)	0.89 (𝑟=0.02)	<0.0001 (𝑟=0.62)
	TP	<0.0002 (𝑟=0.49)	<0.01 (𝑟=0.34)	<0.0001 (𝑟=−0.56)	0.12 (𝑟=0.22)	<0.0001 (𝑟=−0.61)
	PA	<0.0006 (𝑟=−0.46)	<0.008 (𝑟=−0.36)	<0.0001 (𝑟=0.56)	0.6 (𝑟=−0.08)	<0.0002 (𝑟=0.5)

PT: prothrombin time, INR: international normalized ratio, APTT: activated partial thromboplastin time.
SONACT: sonoclot activated clotting time, CR: clot rate, PF: platelet function, TP: time to peak, PA: peak amplitude.
𝑟: Spearmans rank correlation coefficient.
𝑃 value is significant if <0.05.