Research Article

Influence of the Clinical Status on Stress Reticulocytes, CD 36 and CD 49d of SSFA2 Homozygous Sickle Cell Patients Followed in Abidjan

Table 1

Influence of clinical status on epidemiological, clinical, and biological parameters.

ParametersPainful crisis ( )Steady state ( )
m ± sd (min–max)m ± sd (min–max)

Age13.9 ± 9 (2–37)16.4 ± 11.9 (2–43)0.364
Sex (M/F)1.141.14 0.795
Number of crises/year 2.5 ± 1.01 (1–4)2.3 ± 0.84 (1–4)0.406
Hospitalization days/year 1.4 ± 1.01 (0–6)0.47 ± 0.63 (0–2)0.0002
Transfusions/year0.93 ± 0.52 (0–2)0.43 ± 0.5 (0-1)0.0004
Hb S (%)86.8 ± 5.7 (76–95)86.1 ± 4.5 (73.6–93.6)0.622
Hb F (%) 18.8 ± 5.1 (2.5–23.2)11.5 ± 4.4 (3.9–23.6)0.595
Hb A2 (%)2.3 ± 1.01 (1–4)2.4 ± 0.6 (1.5–4.2)0.599
Red blood cells/μL 2 011 000 ± 698 000 2 593 000 ± 605 000 0.001
Hemoglobin (g/dL) 5.64 ± 1.81 6.98 ± 1.47 0.0024
Hematocrit (%)17.83 ± 5.12 21.01 ± 4.03 0.01
Mean cell volume (fL)91.02 ± 10.94 82.42 ± 11.09 0.004
MCH (pg)28.43 ± 3.15 27.32 ± 3.84 0.224
MCHC (%)31.32 ± 2.2233.15 ± 1.570.0005
Leukocytes/μL23 778 ± 13 038 14 206 ± 11 515 0.004
Neutrophils/μL13 046 ± 6 6855 838 ± 3 013 10−6
Platelets/μL 323 133 ± 159 263 407 867 ± 173 572 0.53

m ± sd (min–max): mean ± standard deviation (minimum–maximum).
MCV: mean cell volume.
MVH: mean cell hemoglobin.
MCHC: mean cell hemoglobin concentration.
: Student’s -test.