Table 1: Summary of results of subjects used to derive 5-MTHF reference intervals.

Females mean (SD); medianMales mean (SD); medianStudent’s -test valueAll mean (SD); median

Age (range)38 (10); 38 (23–60)38 (12); 36 (19–64)0.73038 (11); 37
tHcy (μmol/L)8.4 (1.8); 7.9 9.7 (2.1); 9.7 <0.0018.9 (2.1); 8.9
MMA (nmol/L)116 (93); 101 112 (76); 100 0.794114 (85); 100
Plasma 5-MTHF (nmol/L)19.4 (8.5); 19.118.7 (8.2); 17.8 0.62419.1 (8.3); 18.2
Redcell 5-MTHF (nmol/L)*583 (222); 572 585 (164); 557 0.975586 (197); 560
Whole blood 5-MTHF (nmol/L)618 (229); 592 611 (172); 582 0.838615 (205); 584

Result adjusted for plasma 5-MTHF content.