Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage
Table 1
Levels of procoagulant phospholipids (PPLs), tissue factor activity (TFa), D-Dimer (D-Di), and classical biochemical parameters in the cerebrospinal fluid of different groups of patients with central nervous system pathologies.
Variable ()
Controls
ICH
Bacterial meningitis
Viral meningitis
VD
NDD
31
30
15
13
12
11
Clotting time for PPL assay (sec.) ()
164 (158–174)*
125 (93–147)***
144 (136–165)*+
151 (141–155)*+
134 (132–147)***
142 (135–156)*
TFa (pM/L) ()
0.74 (0.60–0.89)ε
2.36 (1.67–3.21)***
0.76 (0.68–0.83)+ + +
0.84 (0.74–0.92)+ + +
1.33 (1.12–1.60)
0.78 (0.62–0.89)+ + +
D-Di (mg/L) ()
0.40 (0.17–0.58)β
0.82 (0.52–0.98)***
0.51 (0.43–0.59)+
0.44 (0.36–0.51)β+ +
0.54 (0.44–0.62)***
0.36 (0.23–0.52)+ + +
Protein (g/L) ()
0.39 (0.24–0.48)
0.62 (0.44–0.85)β***
0.58 (0.38–0.83)*
0.61 (0.55–0.88)***
0.28 (0.18–0.71)
0.45 (0.44–0.52)
Glucose (mmol/L) ()
3.4 (3.2–3.9)
4.8 (4.1–5.4)***
3.1 (2.1–3.8)+ + +
2.8 (2.6–3.4)+ + +
4.0 (3.5–5.2)
3.6 (3.5–3.7)+
Chloride (mmol/L) ()
125 (124–128)
126 (120–132)
124 (117–132)
122 (120–132)
128 (125–132)
126 (123–128)
Lactate (mmol/L) ()
1.67 (1.40–2.16)
2.93 (2.18–3.21)***
2.60 (2.10–3.76)Γ*
2.77 (2.36–2.88)
2.66 (1.71 −3 .87)*
1.34 (1.30–1.44)
Values are medians (1st and 3rd quartiles); = number of patients enrolled. Global for Kruskal-Wallis test *, versus controls; , , versus ICH Missing values: : 5, : 1, :8, : 4, : 2, : 4. ICH: intracerebral haemorrhage VD: ventricular drainage; NDD: neurodegenerative disease.
