Advances in Hematology / 2014 / Article / Tab 1

Research Article

Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage

Table 1

Levels of procoagulant phospholipids (PPLs), tissue factor activity (TFa), D-Dimer (D-Di), and classical biochemical parameters in the cerebrospinal fluid of different groups of patients with central nervous system pathologies.

Variable ( )ControlsICHBacterial meningitisViral meningitisVDNDD

313015131211
Clotting time for PPL assay (sec.)
( )
164 (158–174)*125 (93–147)***144 (136–165)*+151 (141–155)*+134 (132–147)***142 (135–156)*
TFa (pM/L)
( )
0.74 (0.60–0.89)ε2.36 (1.67–3.21)***0.76 (0.68–0.83)+ + +0.84 (0.74–0.92)+ + +1.33 (1.12–1.60)0.78 (0.62–0.89)+ + +
D-Di (mg/L)
( )
0.40 (0.17–0.58)β0.82 (0.52–0.98)***0.51 (0.43–0.59)+0.44 (0.36–0.51)β+ +0.54 (0.44–0.62)*** 0.36 (0.23–0.52)+ + +
Protein (g/L)
( )
0.39 (0.24–0.48)0.62 (0.44–0.85)β***0.58 (0.38–0.83)*0.61 (0.55–0.88)***0.28 (0.18–0.71)0.45 (0.44–0.52)
Glucose (mmol/L)
( )
3.4 (3.2–3.9)4.8 (4.1–5.4)***3.1 (2.1–3.8)+ + +2.8 (2.6–3.4)+ + +4.0 (3.5–5.2)3.6 (3.5–3.7)+
Chloride (mmol/L)
( )
125 (124–128)126 (120–132)124 (117–132)122 (120–132)128 (125–132)126 (123–128)
Lactate (mmol/L)
( )
1.67 (1.40–2.16) 2.93 (2.18–3.21)***2.60 (2.10–3.76)Γ*2.77 (2.36–2.88) 2.66 (1.71 −3 .87)*1.34 (1.30–1.44)

Values are medians (1st and 3rd quartiles); = number of patients enrolled.
Global for Kruskal-Wallis test * , versus controls; , , versus ICH Missing values: : 5, : 1, :8, : 4, : 2, : 4.
ICH: intracerebral haemorrhage VD: ventricular drainage; NDD: neurodegenerative disease.