Table 4: Toxicity profile difference between 2 regimens during induction.

ToxicityaBFM 90-HR (%)aBFM standard (%) value

Neutropenia
 GI-II60700.049
 GIII-IV40300.049
Thrombocytopenia GIV40250.003
Mucositis GIII-GIV30200.005
Thrombotic events760.010
Liver impairment
 Elevated bilirubin37200.001
 Elevated enzyme28110.003