Therapy with Interleukin-22 Alleviates Hepatic Injury and Hemostasis Dysregulation in Rat Model of Acute Liver Failure

<table>Levels of proinflammatory mediators; tumor necrosis factor-<i>α</i> (TNF-<i>α</i>), and cyclooxygenase-2 (COX-2), in the liver tissues. GI: control group, GII: D-GalN/LPS group, and GIII: D-GalN/LPS + IL-22 group. Values are represented as mean <svg height="9.5625" id="M16" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 10.1 9.5625" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> SD. *<svg height="11.375" id="M17" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control group; <sup>#</sup><svg height="11.375" id="M18" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus D-GalN/LPS untreated group.</table>

Advances in Hematology

fig3

Figure 3

Figure 3: Therapy with Interleukin-22 Alleviates Hepatic Injury and Hemostasis Dysregulation in Rat Model of Acute Liver Failure 