Table of Contents Author Guidelines Submit a Manuscript
Advances in Hematology
Volume 2014, Article ID 924030, 5 pages
http://dx.doi.org/10.1155/2014/924030
Research Article

Absence of Association between CCR5 rs333 Polymorphism and Childhood Acute Lymphoblastic Leukemia

1Laboratory of Study and Application of DNA Polymorphisms, Department of Pathological Sciences, Biological Sciences Center, State University of Londrina, Rodovia Celso Garcia Cid, (PR 445), Km 380, 86051-970 Londrina, PR, Brazil
2Laboratory of Hematology, Department of Pathology, Clinical and Toxicological Analysis, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil

Received 27 January 2014; Revised 19 March 2014; Accepted 21 March 2014; Published 13 April 2014

Academic Editor: Helen A. Papadaki

Copyright © 2014 Carlos Eduardo Coral de Oliveira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Belson, B. Kingsley, and A. Holmes, “Risk factors for acute leukemia in children: a review,” Environmental Health Perspectives, vol. 115, no. 1, pp. 138–145, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. INCA, Estimate 2014: Cancer Incidence in Brazil, INCA, Rio de Janeiro, Brazil, 2013.
  3. F. Balkwill, “Cancer and the chemokine network,” Nature Reviews Cancer, vol. 4, no. 7, pp. 540–550, 2004. View at Google Scholar · View at Scopus
  4. J. Vandercappellen, J. Van Damme, and S. Struyf, “The role of CXC chemokines and their receptors in cancer,” Cancer Letters, vol. 267, no. 2, pp. 226–244, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. D. Aldinucci and A. Colombatti, “The inflammatory chemokine CCL5 and cancer progression,” Mediators of Inflammation, vol. 2014, Article ID 292376, 12 pages, 2014. View at Publisher · View at Google Scholar
  6. C. J. Raport, J. Gosling, V. L. Schweickart, P. W. Gray, and I. F. Charo, “Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1β, and MIP-1α,” Journal of Biological Chemistry, vol. 271, no. 29, pp. 17161–17166, 1996. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Samson, O. Labbe, C. Mollereau, G. Vassart, and M. Parmentier, “Molecular cloning and functional expression of a new human CC-chemokine receptor gene,” Biochemistry, vol. 35, no. 11, pp. 3362–3367, 1996. View at Publisher · View at Google Scholar · View at Scopus
  8. P. Proost, A. Wuyts, and J. van Damme, “The role of chemokines in inflammation,” Clinical and Experimental Medicine, vol. 26, no. 4, pp. 211–223, 1996. View at Google Scholar · View at Scopus
  9. P. Spagnolo, E. A. Renzoni, A. U. Wells et al., “C-C chemokine receptor 5 gene variants in relation to lung disease in sarcoidosis,” American Journal of Respiratory and Critical Care Medicine, vol. 172, no. 6, pp. 721–728, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. E.-M. Weiss, A. Schmidt, D. Vobis et al., “Foxp3-mediated suppression of cd95l expression confers resistance to activation-induced cell death in regulatory T cells,” Journal of Immunology, vol. 187, no. 4, pp. 1684–1691, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. C.-H. Tang, A. Yamamoto, Y.-T. Lin, Y.-C. Fong, and T.-W. Tan, “Involvement of matrix metalloproteinase-3 in CCL5/CCR5 pathway of chondrosarcomas metastasis,” Biochemical Pharmacology, vol. 79, no. 2, pp. 209–217, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J.-Y. Chuang, W.-H. Yang, H.-T. Chen et al., “CCL5/CCR5 axis promotes the motility of human oral cancer cells,” Journal of Cellular Physiology, vol. 220, no. 2, pp. 418–426, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. E. Menu, E. De Leenheer, H. De Raeve et al., “Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model,” Clinical and Experimental Metastasis, vol. 23, no. 5-6, pp. 291–300, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. J. C. Aster, W. S. Pear, and S. C. Blacklow, “Notch signaling in leukemia,” Annual Review of Pathology: Mechanisms of Disease, vol. 3, pp. 587–613, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. L. Mirandola, M. Chiriva-Internati, D. Montagna et al., “Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia,” Journal of Pathology, vol. 226, no. 5, pp. 713–722, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Makishima, T. Ito, N. Asano et al., “Significance of chemokine receptor expression in aggressive NK cell leukemia,” Leukemia, vol. 19, no. 7, pp. 1169–1174, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. H. Makishima, T. Ito, K. Momose et al., “Chemokine system and tissue infiltration in aggressive NK-cell leukemia,” Leukemia research, vol. 31, no. 9, pp. 1237–1245, 2007. View at Google Scholar
  18. S. M. Davies, M. J. Borowitz, G. L. Rosner et al., “Pharmacogenetics of minimal residual disease response in children with B-precursor acute lymphoblastic leukemia: a report from the children's oncology group,” Blood, vol. 111, no. 6, pp. 2984–2990, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. D. H. McDermott, P. A. Zimmerman, F. Guignard, C. A. Kleeberger, S. F. Leitman, and P. M. Murphy, “CCR5 promoter polymorphism and HIV-1 disease progression,” The Lancet, vol. 352, no. 9131, pp. 866–870, 1998. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Chelli and M. Alizon, “Determinants of the trans-dominant negative effect of truncated forms of the CCR5 chemokine receptor,” Journal of Biological Chemistry, vol. 276, no. 50, pp. 46975–46982, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. E. M. V. Reiche, M. A. E. Watanabe, A. M. Bonametti et al., “Frequency of CCR5-Δ32 deletion in human immunodeficiency virus type 1 (HIV-1) in healthy blood donors, HIV-1-exposed seronegative and HIV-1-seropositive individuals of southern Brazilian population,” International Journal of Molecular Medicine, vol. 22, no. 5, pp. 669–675, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. A. P. Galvani and J. Novembre, “The evolutionary history of the CCR5-Delta32 HIV-resistance mutation,” Microbes and Infection, vol. 7, no. 2, pp. 302–309, 2005. View at Google Scholar · View at Scopus
  23. P. Weitzenfeld and A. Ben-Baruch, “The chemokine system, and its CCR5 and CXCR4 receptors, as potential targets for personalized therapy in cancer,” Cancer Letters, 2013. View at Publisher · View at Google Scholar
  24. C. Kucukgergin, F. K. Isman, S. Dasdemir et al., “The role of chemokine and chemokine receptor gene variants on the susceptibility and clinicopathological characteristics of bladder cancer,” Gene, vol. 511, no. 1, pp. 7–11, 2012. View at Google Scholar
  25. V. R. Arruda, C. E. Grignolli, M. S. Gonçalves et al., “Prevalence of homozygosity for the deleted alleles of glutathione S-transferase mu (GSTM1) and theta (GSTT1) among distinct ethnic groups from Brazil: relevance to enviromental carcinogenesis?” Clinical Genetics, vol. 54, no. 3, pp. 210–214, 1998. View at Google Scholar · View at Scopus
  26. F. C. Parra, R. C. Amado, J. R. Lambertucci et al., “Color and genomic ancestry in Brazilians,” Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 1, pp. 177–182, 2003. View at Google Scholar
  27. J. S. Maier-Moore, C. A. Cañas, G. Tobón et al., “The CCR5 delta 32 polymorphism (rs333) is not associated with Sjogren's syndrome or type 1 diabetes in colombians,” Clinical Immunology, vol. 148, no. 2, pp. 206–208, 2013. View at Google Scholar
  28. S. M. Muxel, S. D. Borelli, M. K. Amarante et al., “Association study of CCR5 delta 32 polymorphism among the HLA-DRB1 Caucasian population in northern Paraná, Brazil,” Journal of Clinical Laboratory Analysis, vol. 22, no. 4, pp. 229–233, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. K. Brajão de Oliveira, E. M. Vissoci Reiche, H. Kaminami Morimoto et al., “Analysis of the CC chemokine receptor 5 delta32 polymorphism in a Brazilian population with cutaneous leishmaniasis,” Journal of Cutaneous Pathology, vol. 34, no. 1, pp. 27–32, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. M. N. Aoki, A. C. D. S. do Amaral Herrera, M. K. Amarante, J. L. do Val Carneiro, M. H. P. Fungaro, and M. A. E. Watanabe, “CCR5 and p53 codon 72 gene polymorphisms: implications in breast cancer development,” International Journal of Molecular Medicine, vol. 23, no. 3, pp. 429–435, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. N. Degerli, E. Yilmaz, and F. Bardakci, “The Δ32 allele distribution of the CCR5 gene and its relationship with certain cancers in a Turkish population,” Clinical Biochemistry, vol. 38, no. 3, pp. 248–252, 2005. View at Publisher · View at Google Scholar · View at Scopus
  32. K. Guleria, S. Sharma, M. Manjari et al., “p.R72P, PIN3 Ins16bp polymorphisms of TP53 and CCR5?32 in north Indian breast cancer patients,” Asian Pacific Journal of Cancer Prevention, vol. 13, no. 7, pp. 3305–3311, 2012. View at Google Scholar
  33. A. Zafiropoulos, N. Crikas, A. M. Passam, and D. A. Spandidos, “Significant involvement of CCR2-64I and CXCL12-3a in the development of sporadic breast cancer,” Journal of Medical Genetics, vol. 41, no. 5, p. e59, 2004. View at Google Scholar · View at Scopus
  34. D. T. Teachey and S. P. Hunger, “Predicting relapse risk in childhood acute lymphoblastic leukaemia,” British Journal of Haematology, vol. 162, no. 5, pp. 606–620, 2013. View at Google Scholar
  35. A. de Lourdes Perim, R. L. Guembarovski, J. M. Oda et al., “CXCL12 and TP53 genetic polymorphisms as markers of susceptibility in a Brazilian children population with acute lymphoblastic leukemia (ALL),” Molecular Biology Reports, vol. 40, no. 7, pp. 4591–4596, 2013. View at Google Scholar