Research Article
Predictors of Outcome and Severity in Adult Filipino Patients with Febrile Neutropenia
Table 1
Baseline clinical characteristics of febrile neutropenia cases.
| | Clinical parameter | Outcome frequency (%) | Complicated group
(50.4) | Noncomplicated group
(49.6) |
| | Age | | | | Mean (SD) | 41.24 (15.99) | 40 (11.89) | | Median | 40.5 | 42 | | Range | 19–71 | 19–61 | | Sex | | | | Male | 23 (39.7) | 24 (42.1) | | Female | 35 (60.3) | 33 (57.9) | | Primary underlying disease | | | | Leukemia | 29 (50) | 27 (47.4) | | Lymphoma (all sites) | 1 (1.7) | 1 (1.8) | | Solid-organ tumor | 9 (15.5) | 18 (31.6) | | Bone marrow failure state | 6 (10.3) | 3 (5.2) | | Others | 13 (22.4) | 8 (14.0) | | Comorbid | | | | None | 41 (70.7) | 43 (7.5) | | Cardiovascular disease | 8 (13.8) | 13 (22.8) | | Pulmonary disease | 1 (1.7) | 0 | | Liver disease | 0 | 1 (1.8) | | Renal disease | 3 (5.2) | 0 | | Diabetes mellitus | 2 (3.4) | 0 | | Others | 3 (5.2) | 0 | | Outcome | | | | Discharged improved | 32 (60.3) | 57 (100.0) | | Expired | 22 (37.9) | 0 | | Left against advice | 4 (6.9) | 0 | | Status of treatment | | | | Treated/on treatment | 32 (55.2) | 40 (70.2) | | Remission | 0 | 2 (3.5) | | Relapse | 3 (5.2) | 3 (5.3) | | Not on treatment | 23 (39.7) | 12 (21) | | Type of treatment | | | | Chemotherapy | 26 (44.8) | 28 (49.1) | | Combination therapy | 6 (10.3) | 17 (29.8) | | None | 26 (44.8) | 12 (21.1) | | G-CSF use | | | | Yes | 16 (27.6) | 23 (40.3) | | No | 42 (72.4) | 34 (59.7) | | Duration of fever prior to admission | | | | 7 days | 42 (72.4) | 51 (89.5) | | 7 days | 16 (27.6) | 6 (10.5) | | Duration of neutropenia during admission | | | | 7 days | 27 (46.6) | 35 (61.4) | | 7 days | 31 (53.4) | 22 (39.6) | | Recovery from neutropenia | | | | Yes | 17 (29.3) | 27 (47.4) | | No | 41 (70.7) | 30 (52.6) |
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