Haploidentical Stem Cell Transplantation in Adult Haematological Malignancies

Figure 1

Conditioning regimen used for nonmyeloablative haploidentical transplantation, using high dose cyclophosphamide (Cy) posttransplant for in vitro T cell depletion. Pretransplant conditioning involved Cy, fludarabine, and TBI, with administration of high dose Cy on day 3 (or days 3 and 4) after transplantation. GVHD prophylaxis consisting of tacrolimus and MMF was initiated after Cy. BMT: bone marrow transplantation, Cy: cyclophosphamide, TBI: total body irradiation, G-CSF: granulocyte colony stimulating factor, and MMF: mycophenolate mofetil.