Research Article

Glucose-6-Phosphate Dehydrogenase Deficiency and Sickle Cell Trait among Prospective Blood Donors: A Cross-Sectional Study in Berekum, Ghana

Table 6

Logistic regression of factors associated with sickle haemoglobin variant (AS).

ParametersOR (95% CI) value

Age group
18–290.229 (0.014–3.826)0.305
30–390.250 (0.015–4.217)0.336
40–490.231 (0.011–4.838)0.345
50–59Reference
Sex
Male0.711 (0.183–2.758)0.621
FemaleReference
G6PD status
NormalReference
Partial defect5.029 (5.029)
Full defect3.627 (1.630–8.067)0.002
G6PD activity
Mild deficiency2.410 (1.049–5.534)0.038
Nondeficient0.676 (0.273–1.676)0.398
Increased activityReference
Donor type
Commercial5.609 (1.309–24.035)0.020
Voluntary2.404 (1.071–5.397)0.034
ReplacementReference

OR: odds ratio; CI: confidence interval.