Research Article

Frequency of Red Blood Cell Alloimmunization in Patients with Sickle Cell Disease in Palestine

Table 1

SCD patients’ demographic and transfusion characteristics in Palestine.

VariableSCD alloimmunizedSCD nonimmunizedTotalP-value

n (%)9 (7.76%)107 (92.24%)116 (100)- -

Age (years), (Mean ± SD)24.0 ± 10.9918.4 ± 9.66- -- -

Number of transfused units, (Mean ± SD)53.3 ± 22.227.7 ± 17.629.7 ± 19.10.019 (S)

Sex, n (%):0.73 (NS)
 Male4 (6.3)59 (93.7)63 (100)
 Female5 (9.4)48 (90.6)53 (100)

Age distribution in years, n (%):0.001 (S)
 Child (< 14)1 (1.4%)72 (98.6%)73 (100%)
 Adult (> 14)8 (18.6)35 (81.4)43 (100%)

Type of hemoglobin, n (%):0.73 (NS)
 HbSS4 (6.45)58 (93.55)62 (100)
 S/B-thal5 (9.26)49 (90.74)54 (100)

Splenomegaly, n (%):0.009 (S)
 Yes7 (28)18 (72)25 (100)
 No2 (2.2)89 (97.8)91 (100)