Table 3: Characteristics of alloimmunized SCD patients (HbSS and HbS/β-thal).

Patient No.SexAge(years)HemoglobinopathyNo. of blood units transfusedAlloantibody detectedIndication for transfusionTransfusion reaction

1F20HbSS73Anti-KAnemia, Hb< 7g/dlNo

2M48HbSS98Ant-C + DPainful crisis,
anemia
DHTR1,
jaundice

3F31HbSS57Anti-KPainful crisis, anemiaDHTR,
jaundice

4M24HbSS48Anti-CJoint pain,
painful crisis
Anemia
No

5M8HbS/ β-Thal.20Anti-DAnemia, Hb< 8g/dlIHTR2,
jaundice

6F18HbS/ β-Thal.42Anti-EAnemia, joint painNo

7F26HbS/ β-Thal.51Anti-KAnemia, Hb< 6g/dlJaundice

8M22HbS/ β-Thal.54Anti-EAnemia, painful crisisNo

9M19HbS/ β-Thal.37Anti-cAnemia, painful crisisJaundice

DHTR: delayed hemolytic transfusion reactions; 2IHTR: immediate hemolytic transfusion reaction.