Research Article

Regulatory T Cells and Profile of FOXP3 Isoforms Expression in Peripheral Blood of Patients with Myelodysplastic Syndromes

Table 3

The absolute number of cell populations in the peripheral blood of patients with MDS and age-matched healthy donors (109 cells/L).

GroupLeukocytesLymphocytesCD4+ Т cells

Age control, n=266.15 (5.4–7.7)2.0 (1.7–2.4)0.8 (0.6–1.0)
MDS-primary1, n=214.1 (3.0–5.8)1.6 (1.2–2.6)0.5 (0.4–0.9)
E-MDS2, n=273.1 (2.0–3.9)1.2 (0.9–1.5)0.4 (0.3–0.6)
L-MDS3, n=282.6 (1.7–3.9)1.1 (0.8–2.1)0.4 (0.2–0.6)

Note: p<0.05 rel. to age control; p<0.001 rel. to age control; p<0.05 rel. to MDS-primary. 1MDS-primary, primary myelodysplastic syndrome; 2E-MDS, early-stage myelodysplastic syndrome; 3L-MDS, late-stage myelodysplastic syndrome.