Regulatory T Cells and Profile of FOXP3 Isoforms Expression in Peripheral Blood of Patients with Myelodysplastic Syndromes

Table 4

The absolute number and percentage of regulatory T cells in the peripheral blood of patients with MDS and age-matched healthy donors.

Group	Treg, 10^6 cells/L	Percentage of Treg among CD4^+ T cells, %
Age control, n=26	29.8 (23.3–40.2)	4.1 (3.4–4.3)
MDS-primary^1, n=21	17.0 (12.0–19.7)	3.2 (2.7–4.0)
E-MDS^2, n=27	13.6 (7.9–19.9)	3.1 (1.8–4.7)
L-MDS^3, n=28	12.6 (8.0–17.3)	3.6 (2.8–5.8)

Note: p<0.05 rel. to age control; p<0.001 rel. to age control. ¹MDS-primary, primary myelodysplastic syndrome; ²E-MDS, early-stage myelodysplastic syndrome; ³L-MDS, late-stage myelodysplastic syndrome.