Advances in Hematology / 2018 / Article / Tab 5

Research Article

Regulatory T Cells and Profile of FOXP3 Isoforms Expression in Peripheral Blood of Patients with Myelodysplastic Syndromes

Table 5

The ratio of FOXP3 exon 2 fluorescence intensity to FOXP3 total fluorescence intensity in CD3+CD4+FOXP3+ cells from the peripheral blood of the patients with MDS and age-matched healthy donors.

GroupFI (FOXP3 exon 2/total), a.u.4

Age control, n=260.52 (0.48–0.56)
MDS-primary1, n=210.68 (0.59–0.75)
E-MDS2, n=270.56 (0.47–0.65)
L-MDS3, n=280.54 (0.47–0.62)

-primary: primary myelodysplastic syndrome; 2E-MDS: early-stage myelodysplastic syndrome; 3L-MDS: late-stage myelodysplastic syndrome; 4a.u.: arbitrary units. Note: p<0.001 rel. to age control; p<0.05 rel. to MDS-primary; p <0.001 rel. MDS-primary.