Research Article
Lung Function Abnormalities in Sickle Cell Anaemia
Table 6
Comparisons of means of laboratory results and TRV with spirometry outcomes among Hb-SS subjects.
| | Spirometry Interpretation | | | Obstructive | Restrictive | Mixed | Normal | P-value |
| | Hemoglobin Level (g/dl) | 8.4±1.8 | 7.9±1.6 | 7.3±2.0 | 8.4±1.3 | 0.350 | | Total Neutrophil count (x 109/l) | 8.5±3.2 | 10.6±4.0 | 8.3±1.2 | 10.3±3.3 | 0.413 | | Platelet Count (x 109/l) | 251.1±58.9 | 366.6±103.1 | 308.4±87.8 | 350.6±127...3 | 0.034 | | Plasma Haemoglobin (ug/ml) | 94.8±46.8 | 132.4±81.3 | 99.7±34.5 | 115.9±83.3 | 0.699 | | Creatinine | 64.8±17.3 | 57.8±22.8 | 61.7±28.0 | 49.4±10.8 | 0.372 | | Urea | 3.1±0.5 | 3.9±2.0 | 4.1±2.1 | 2.9±0.6 | 0.203 | | FVC% | 87.6 ±15.6 | 61.4±11.4 | 57.3±11.6 | 94.1±16.4 | <0.001 | | FEV1% | 61.8 ±12.3 | 56.9±11.2 | 43.0±9.6 | 88.1±18.4 | <0.001 | | Freq of crisis/year | 0.5±0.8 | 1.5±1.3 | 1.1±0.9 | 1.1±1.4 | 0.410 | | TRV(m/s) | 2.4±0.3 | 2.3±0.4 | 2.6±0.4 | 2.2±0.4 | 0.056 |
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