Research Article
Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia
Table 1
Criteria for assessment of morphological response.
| Parameter | Finding | Points |
| Cellularity | not increased for age | 0 | increased for age | 1 |
| M:E ratio | ≤ 4:1 | 0 | > 4:1 | 1 |
| Fibrosis | grades 0 to 2 | 0 | grade 3 | 1 |
| Abnormal megakaryocytes | < 10% of all megakaryocytes | 0 | ≥ 10% of all megakaryocytes | 1 |
| Type of tap | not dry | 0 | dry | 1 |
| Percentage of blasts | dry tap | 0 | not dry and < 5% | 0 | not dry and ≥ 5% | 1 |
| Percentage of basophils | dry tap | 0 | not dry and < 1% | 0 |
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M:E ratio: myeloid: erythroid ratio.
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