Research Article

Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia

Table 1

Criteria for assessment of morphological response.

ParameterFindingPoints

Cellularitynot increased for age0
increased for age1

M:E ratio≤ 4:10
> 4:11

Fibrosisgrades 0 to 20
grade 31

Abnormal megakaryocytes< 10% of all megakaryocytes0
≥ 10% of all megakaryocytes1

Type of tapnot dry0
dry1

Percentage of blastsdry tap0
not dry and < 5%0
not dry and ≥ 5%1

Percentage of basophilsdry tap0
not dry and < 1%0

M:E ratio: myeloid: erythroid ratio.