Research Article
Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia
Table 3
Bone marrow morphology findings at the time of diagnosis and at 3 months after treatment follow-up.
| Morphological parameter | At the time of diagnosis | At 3 months of follow-up | (N=31) | (N=29) |
| Increased cellularity | 31 (100%) | 4 (13.79%) |
| M:E ratio > 4:1 | 31 (100%) | 4 (13.79%) |
| Abnormal megakaryocytes | 31 (100%) | 5 (17.24%) |
| Fibrosis | Grade 0 | 0 | 6 (20.69%) | Grade 1 | 4 (12.9%) | 12 (41.38%) | Grade 2 | 19 (61.29%) | 9 (31.03%) | Grade 3 | 8 (25.80%) | 2 (6.89%) |
| Blast count > 5 | 10 (32.25%) | 1 (3.44%) |
| Basophils > 1 | 22 (70.96%) | 5 (17.24%) |
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M:E ratio: myeloid: erythroid ratio
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