Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia

Table 3

Bone marrow morphology findings at the time of diagnosis and at 3 months after treatment follow-up.

Morphological parameter		At the time of diagnosis	At 3 months of follow-up
		(N=31)	(N=29)
Increased cellularity		31 (100%)	4 (13.79%)
M:E ratio > 4:1		31 (100%)	4 (13.79%)
Abnormal megakaryocytes		31 (100%)	5 (17.24%)
Fibrosis	Grade 0	0	6 (20.69%)
	Grade 1	4 (12.9%)	12 (41.38%)
	Grade 2	19 (61.29%)	9 (31.03%)
	Grade 3	8 (25.80%)	2 (6.89%)
Blast count > 5		10 (32.25%)	1 (3.44%)
Basophils > 1		22 (70.96%)	5 (17.24%)

M:E ratio: myeloid: erythroid ratio