Research Article

Changes in Blood Profile from Steady State in Patients with Sickle Cell Anemia Admitted for Vaso-occlusive Crisis and Acute Chest Syndrome

Table 1

Numerical change and analysis from steady state between VOC admission and VOC admission complicated by ACS.

LabSample sizeMean difference in ACS admission and steady stateMean difference in VOC admission and steady stateDifference between ACS and VOC95% confidence interval value
B-H value

WBC count (K cells/μL)436.84.12.71 (±7.62)[0.36, 5.05]0.025
0.058
ANC (K cells/μL)396.03.72.27 (±6.77)[0.77, 4.47]0.043
0.058
Platelet count (K cells/μL)40−108.0−44.0−63.90 (±164.4)[−116.44, −11.31]0.019
0.058
AEC (K cells/μL)37−0.07−0.160.89 (±0.42)[−0.05, 0.23]0.212
0.294
Hgb41−0.67−0.35−0.32 (±1.75)[−0.87, 0.23]0.252
0.294
ARC (K cells/μL)340.060.050.006 (±0.15)[−0.05, 0.06]0.827
0.827
Oxygen saturation (%)27−2.20−0.26−1.96 (±3.73)[−3.44, −0.49]0.011
0.058

Significant by Benjamini–Hochberg false discovery rate.