Research Article

Blood Donors’ Age, Haemoglobin Type, G6PD Status, and Blood Group Impact Storability of CPDA-1 Banked Whole Blood: A Repeated-Measure Cohort Study in Cape Coast, Ghana

Table 3

Stratification based on the qualitative G6PD status.

VariableDays value
Day 0Day 7Day 14Day 21Day 35

Plasma K+ levels
G6PDd4.0509.72013.75016.71023.820<0.0001
G6PD normal4.04010.20014.94017.65023.830<0.0001
valuensnsnsnsns

Osmotic-induced lysis
G6PDdND74.94037.06027.64042.340<0.0001
G6PD normalND81.94054.93040.40050.880<0.0001
valuensnsns0.0438

% free haemoglobin
G6PDdND0.0000.0000.64400.980<0.0001
G6PD normalND0.0000.0000.5900.880<0.0001
valuensnsnsns

ND means not determined; ns means not significant; median value significantly differed from day 0 (K+ levels), or day 7 (for osmotic fragility or % free haemoglobin); ns means not statistically significantly different; statistical significance was estimated per each G6PD status in relation to days of storage by means of Friedman’s repeated measure test with Dunn’s multiple correction; across the two G6PD stratification, statistical differences within each day were calculated using the Mann–Whitney test.