Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pilot Study
Table 2
Initial blood parameters and therapeutic process depending on dental as well as periodontal treatment need.
Parameter
Periodontal treatment need
Dental treatment need
Yes (n = 25)
No (n = 9)
value
Yes (n = 29)
No (n = 10)
value
Initial blood parameters
CRP (mg/l)
41.9 ± 41.7
21.1 ± 17.6
0.48
40.3 ± 39.7
46.8 ± 90.7
0.21
LDH (U/I)
642.6 ± 679.9
795.8 ± 1116.9
0.73
723.2 ± 870.4
597.8 ± 438.5
0.71
aPTT (sec)
28.4 ± 6.5
28.6 ± 2.7
0.90
29.1 ± 6.8
28.0 ± 3.6
0.58
Hemoglobin (g/dl)
9.8 ± 1.3
10.7 ± 2.3
0.29
10.1 ± 1.6
10.0 ± 1.6
0.95
Hematocrit (%)
28.6 ± 4.3
31.3 ± 6.8
0.29
29.6 ± 4.9
29.1 ± 5.3
0.78
Initial therapy parameters
Erythrocytes (10³/μl)
Initial
3.2 ± 0.6
3.5 ± 0.9
0.51
3.4 ± 0.7
3.2 ± 0.6
0.31
3 days
3.4 ± 1.2
2.5 ± 1.7
0.85
3.1 ± 0.9
4.0 ± 1.9
0.14
7 days
2.9 ± 0.5
2.4 ± 1.6
0.21
3.1 ± 1.0
2.9 ± 0.7
0.33
Thrombocytes (10³/μl)
Initial
66.4 ± 69.1
153.4 ± 136.9
0.07
67.7 ± 76.0
145.4 ± 133.6
0.12
3 days
59.5 ± 52.8
147.4 ± 135.4
0.19
68.0 ± 77.7
118.3 ± 110.2
0.63
7 days
43.0 ± 44.5
131.3 ± 108.5
0.03
53.2 ± 67.1
83.3 ± 83.6
0.50
Leukocytes (10³/μl)
Initial
18.4 ± 35.7
35.3 ± 59.7
0.31
25.2 ± 46.3
15.3 ± 24.1
0.50
3 days
14.4 ± 27.6
31.1 ± 65.5
0.77
19.9 ± 41.2
19.2 ± 41.0
0.89
7 days
6.9 ± 15.3
10.8 ± 12.1
0.07
8.3 ± 15.6
2.7 ± 3.2
0.82
CRP (mg/l) max
155.0 ± 95.1
102.4 ± 97.4
0.23
149.7 ± 88.4
198.2 ± 145.0
0.39
Duration of erythropenia in days
38.6 ± 22.6
28.7 ± 22.4
0.33
38.0 ± 21.4
40.0 ± 31.5
0.83
Duration of thrombopenia in days
31.7 ± 19.4
23.1 ± 16.9
0.28
29.6 ± 17.7
29.3 ± 23.0
0.97
Duration of leukopenia in days
26.8 ± 18.9
15.1 ± 11.1
0.09
23.5 ± 17.4
25.6 ± 18.2
0.59
Duration of neutropenia in days
15.9 ± 16.7
6.4 ± 7.9
0.11
13.6 ± 15.4
16.9 ± 15.3
0.49
Duration of fever in days
13.0 ± 13.0
9.3 ± 9.7
0.45
9.1 ± 7.8
25.8 ± 22.5
0.06
Positive microbiological findings
Blood
12/20 (60%)
2/5 (40%)
0.62
13/23 (57%)
5/6 (83%)
0.36
Urine
13/21 (62%)
0/3 (0%)
0.08
9/20 (45%)
6/7 (86%)
0.09
CRP: C-reactive protein, LDH: lactate dehydrogenase, aPTT: activated Partial Thromboplastin Time, significant results are highlighted in bold ().
