Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pilot Study
Table 3
Initial blood parameters and therapeutic process depending on PISA.
Parameter
PISA
>98 mm2 (n = 17)
≤98 mm2 (n = 17)
value
Initial blood parameters
CRP (mg/l)
35.4 ± 40.8
38.9 ± 36.6
0.53
LDH (U/I)
610.3 ± 789.3
760.9 ± 817.6
0.18
aPTT (sec)
29.5 ± 2.4
27.6 ± 7.5
0.13
Hemoglobin (g/dl)
9.5 ± 1.3
10.5 ± 2.0
0.06
Hematocrit (%)
27.8 ± 3.6
30.8 ± 6.0
0.09
Initial therapy parameters
Erythrocytes (10³/μl)
Initial
3.1 ± 0.5
3.5 ± 0.8
0.13
3 days
3.0 ± 0.5
3.9 ± 1.5
0.01
7 days
2.9 ± 0.4
3.4 ± 1.0
0.25
Thrombocytes (10³/μl)
Initial
73.4 ± 76.3
104.8 ± 115.1
0.72
3 days
61.1 ± 50.6
101.6 ± 111.7
0.56
7 days
42.0 ± 34.7
79.3 ± 90.5
0.31
Leukocytes (10³/μl)
Initial
13.2 ± 28.7
32.5 ± 52.9
0.34
3 days
14.0 ± 31.0
22.6 ± 46.2
0.72
7 days
8.5 ± 18.6
6.9 ± 9.7
0.31
CRP (mg/l) max
135.2 ± 101.6
153.0 ± 93.2
0.61
Duration of erythropenia in days
30.6 ± 19.7
43.1 ± 24.5
0.09
Duration of thrombopenia in days
28.6 ± 19.2
31.2 ± 19.3
0.70
Duration of leukopenia in days
26.6 ± 20.7
21.6 ± 14.6
0.65
Duration of neutropenia in days
16.3 ± 18.3
11.1 ± 11.8
0.47
Duration of fever in days
8.9 ± 8.1
15.4 ± 15.1
0.17
Positive microbiological findings
Blood
7/14 (50%)
7/11 (64%)
0.69
Urine
7/14 (50%)
6/10 (60%)
0.70
CRP: C-reactive protein, LDH: lactate dehydrogenase, aPTT: activated Partial Thromboplastin Time, significant results are highlighted in bold ().