Thrombophilic Risk of Factor V Leiden, Prothrombin G20210A, MTHFR, and Calreticulin Mutations in Essential Thrombocythemia Egyptian Patients

Table 3

Multivariate analysis of thrombotic risk of ET patients.

	Thrombosis		Odds ratio (confidence interval)
	Present	Absent
Factor V Leiden	30 (25	24 (20%)	5.625 (2.3–13.9)	0.014
Prothrombin gene mutation	18 (15%)	9 (7.5%)	5.750 (3.1–15.8)	0.02
MTHFR mutation	30 (25%)	63 (52.5%)	0.595 (1.0–2.5)	0.1
JAK2 V617F mutation	27 (22.5%)	51 (42.5%)	0.95 (0.6–2.8)	0.9
CALR mutation	9 (7.5%)	5 (4.1%)	4.7 (2.9–10.9)	0.04
CVS risk factors (at least one)	36 (30%)	30 (25%)	2.9 (1.1–5.1)	0.1