Research Article

Laboratory Biomarkers, Cerebral Blood Flow Velocity, and Intellectual Function in Children with Sickle Cell Disease

Table 2

Correlations between biomarkers, TCD, and IQ.

HbFWBCCRPANCTFEPOsVCAMTATdTXB2PlateletReticulocyteLDHBilirubinASTTCDABIQNVIQVIQ

Hgb0.77−0.26−0.12−0.28−0.15−0.53−0.280.05−0.400.35−0.40−0.38−0.24−0.34−0.290.170.130 .13
HbF−0.42−0.14−0.35−0.24−0.46−0.26−0.04−0.140.15−0.40−0.50−0.36−0.41−0.280.080.120.00
WBC0.180.820.03−0.070.240.120.10−0.110.620.230.37−0.010.19−0.11−0.00−0.16
CRP0.07−0.140.210.070.230.07−0.030.20−0.03−0.23−0.120.13−0.12−0.06−0.12
ANC0.020.020.45−0.020.06−0.100.550.170.34−0.000.16−0.17−0.17−0.10
TF0.20−0.28−0.02−0.080.01−0.080.290.070.180.04−0.01−0.220.20
EPO0.21−0.050.34−0.120.110.140.020.370.23−0.18−0.17−0.11
sVCAM.090.15−0.250.360.050.250.200.280.02−0.020.05
TAT0.040.000.33−0.23−0.17−0.200.030.240.160.21
dTXB2−0.250.14−0.150.000.170.19−0.080.14−0.25
Platelet−0.070.030.02−0.03−0.15−0.15−0.13−0.10
Reticulocyte−0.110.410.040.00−0.10−0.06−0.10
LDH0.180.510.40−0.29−0.36−0.09
Bilirubin0.470.03−0.07−0.120.01
AST0.22−0.02−0.110.08
TCD−0.18−0.04−0.23
ABIQ0.760.77
NVIQ0.18