Homozygous Sickle Cell Disease after Age of 40: Follow-Up of a Cohort of 209 Patients in Senegal, West Africa

Table 1

Basic characteristics of SCD patients.

Parameters	Patients over 40 (n = 209)	Patients under 40 (n = 2244)	P
Origin of patients
Dakar (Senegalese capital)	153 (73.2%)	1688 (75.2%)	0.010
Others (Senegalese regions or country)	56 (26.8%)	556 (24.8%)
Sex (sex ratio = 0.6)
Female	130 (62.2%)	1164 (51.9%)	0.031
Male	79 (37.8%)	1079 (48.1%)
Marital status
Married	108 (51.79%)	727 (32.4%)	0.013
Unmarried	94 (44.9%)	1263 (56.3%)
Divorced	7 (3.4%)	253 (11.3%)
Patients with professional activity	186 (88.9%)	525 (23.4%)	0.001
Patients with regular follow-up	58 (27.8%)	1855 (82.7%)	0.010
Patients with comorbidities	47 (22.4%)	219 (9.7%)	0.001
Current vaccination status	27 (12.9%)	1283 (57.2%)	0.030
Therapeutic aspects
Folic acid	206 (99%)	2212 (98.6%)	0.001
Hydroxyurea	3 (1.43%)	34 (1.51%)	0.020