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Advances in Medicine
Volume 2014, Article ID 704875, 6 pages
Research Article

A Study on the Association between Low Maternal Serum Magnesium Level and Preterm Labour

Department of Obstetrics & Gynaecology, Lagos University Teaching Hospital, Lagos, Nigeria

Received 7 January 2014; Revised 18 March 2014; Accepted 24 March 2014; Published 13 April 2014

Academic Editor: Anthony H. Taylor

Copyright © 2014 Kehinde S. Okunade et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. The study was aimed to assess the association between low maternal serum magnesium levels and preterm labour. Methods. It is a cross-sectional case-control study in which eligible participants were pregnant women admitted in labour within the labour ward complex of a Lagos tertiary hospital. Relevant data were extracted from the case records of these women and blood samples were obtained from all participants and serum magnesium levels measured. Results. The study showed that 36% of the study patients had varying degrees of hypomagnesaemia. The relative risk indicates that preterm labour is 1.83 times higher among the patients with low serum magnesium (less than 1.6 mg/dL). The mean difference in serum magnesium levels in both groups was statistically significant (). Conclusion. We can infer that low serum magnesium (hypomagnesaemia) is associated with preterm onset of labour. We can, also from this finding, formulate a proposition that would help in preventing preterm labour and birth with the use of prophylactic oral magnesium supplementation among patients with higher risk for development of preterm labour.