An Association between Single Nucleotide Polymorphisms of Lys751Gln ERCC2 Gene and Ovarian Cancer in Polish Women

Table 2

Genotypes and alleles distributions of SNP Lys751Gln in ERCC2 in ovarian cancer cases versus lean controls.

ERCC2-Lys751Gln	Patients ()		Controls ()		OR (95% CI)
	Number	(%)	Number	(%)
Lys/Lys	62	14.4	96	22.3	1.00 Ref.
Lys/Gln	64	14.9	240	55.8	0.41 (0.27–0.62)	<0.0001
Gln/Gln	304	70.7	94	21.8	5.01 (3.37–7.43)	<0.0001
Lys	188	21.8	432	50.2	1.00 Ref.
Gln	672	78.2	428	49.8	3.61 (2.92–4.45)	<0.0001

Crude odds ratio (OR); 95% CI: confidence interval at 95%; Chi square.