Research Article

The Protective Effects of Alpha-Lipoic Acid and Coenzyme Q10 Combination on Ovarian Ischemia-Reperfusion Injury: An Experimental Study

Table 1

Pathological scoring of all groups.

Apoptosis score
Mean ± std. deviation
Nitric oxide synthase
Mean ± std. deviation
Histopathological evaluation
Mean ± std. deviation

Group 1 (sham) ()Left ovary1.0 ± 0.00.2590.2 ± 0.10.5300.0 ± 0.01.00
Right ovary0.7 ± 0.20.3 ± 0.10.0 ± 0.0

Group 2
Control (saline) ()
Left ovary3.8 ± 0.90.0031.3 ± 0.60.6442.7 ± 0.480.001
Right ovary3.6 ± 0.71.7 ± 0.80.71 ± 0.48

Group 3
Control (olive oil) ()
Left ovary3.7 ± 0.50.0021.7 ± 0.50.3672.8 ± 0.370.001
Right ovary3.6 ± 0.72.0 ± 0.60.85 ± 0.69

Group 4 (ALA) ()Left ovary2.7 ± 1.10.0012.3 ± 1.10.7091.7 ± 0.480.005
Right ovary0.6 ± 0.12.4 ± 1.30.57 ± 0.53

Group 5 (CoQ10) ()Left ovary2.6 ± 1.40.0022.4 ± 1.20.9471.7 ± 0.750.015
Right ovary1.1 ± 0.32.1 ± 0.90.7 ± 0.48

Group 6 (ALA + CoQ10) ()Left ovary2.5 ± 1.30.0082.6 ± 1.40.5781.7 ± 0.480.014
Right ovary0.9 ± 0.12.6 ± 1.50.57 ± 0.78

was accepted to be statistically significant.