Research Article
The Protective Effects of Alpha-Lipoic Acid and Coenzyme Q10 Combination on Ovarian Ischemia-Reperfusion Injury: An Experimental Study
Table 1
Pathological scoring of all groups.
| | | Apoptosis score Mean ± std. deviation | | Nitric oxide synthase Mean ± std. deviation | | Histopathological evaluation Mean ± std. deviation | |
| Group 1 (sham) () | Left ovary | 1.0 ± 0.0 | 0.259 | 0.2 ± 0.1 | 0.530 | 0.0 ± 0.0 | 1.00 | Right ovary | 0.7 ± 0.2 | 0.3 ± 0.1 | 0.0 ± 0.0 |
| Group 2 Control (saline) () | Left ovary | 3.8 ± 0.9 | 0.003 | 1.3 ± 0.6 | 0.644 | 2.7 ± 0.48 | 0.001 | Right ovary | 3.6 ± 0.7 | 1.7 ± 0.8 | 0.71 ± 0.48 |
| Group 3 Control (olive oil) () | Left ovary | 3.7 ± 0.5 | 0.002 | 1.7 ± 0.5 | 0.367 | 2.8 ± 0.37 | 0.001 | Right ovary | 3.6 ± 0.7 | 2.0 ± 0.6 | 0.85 ± 0.69 |
| Group 4 (ALA) () | Left ovary | 2.7 ± 1.1 | 0.001 | 2.3 ± 1.1 | 0.709 | 1.7 ± 0.48 | 0.005 | Right ovary | 0.6 ± 0.1 | 2.4 ± 1.3 | 0.57 ± 0.53 |
| Group 5 (CoQ10) () | Left ovary | 2.6 ± 1.4 | 0.002 | 2.4 ± 1.2 | 0.947 | 1.7 ± 0.75 | 0.015 | Right ovary | 1.1 ± 0.3 | 2.1 ± 0.9 | 0.7 ± 0.48 |
| Group 6 (ALA + CoQ10) () | Left ovary | 2.5 ± 1.3 | 0.008 | 2.6 ± 1.4 | 0.578 | 1.7 ± 0.48 | 0.014 | Right ovary | 0.9 ± 0.1 | 2.6 ± 1.5 | 0.57 ± 0.78 |
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was accepted to be statistically significant.
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