CYP4F2 (rs2108622) Gene Polymorphism Association with Age-Related Macular Degeneration

Table 10

Binomial logistic regression analysis of the CYP4F2 (1347C>T; V433M) rs2108622 in the males with eAMD and in the control group by age.

Model	Genotype	OR (95% CI)	value	AIC
<65
Codominant	T/T	1.583 (0.129; 19.422)	0.719	44.539
	T/C	0.559 (0.091; 3.446)	0.531
Dominant	T/C + T/T	0.713 (0.141; 3.612)	0.682	43.065
Recessive	T/T	2.00 (0.177; 22.550)	0.575	42.948
Overdominant	T/C	0.518 (0.089; 3.002)	0.463	42.662
Additive	—	1.045 (0.298; 3.667)	0.945	43.230
≥65
Codominant	T/T	0.062 (0.005; 0.720)	0.026	53.304
	T/C	0.123 (0.014; 1.108)	0.062
Dominant	T/C + T/T	0.103 (0.012; 0.871)	0.037	51.927
Recessive	T/T	0.248 (0.048; 1.276)	0.095	56.239
Overdominant	T/C	0.417 (0.105; 1.661)	0.215	57.207
Additive	—	3.670 (1.282; 10.502)	0.015	52.149