CYP4F2 (rs2108622) Gene Polymorphism Association with Age-Related Macular Degeneration

Table 9

Binomial logistic regression analysis of the CYP4F2 (1347C>T; V433M) rs2108622 in the males with early AMD and in the control group by age.

Model	Genotype	OR (95% CI)	value	AIC
<65
Codominant	T/T	1.727 (0.296; 10.082)	0.544	97.984
	T/C	1.524 (0.551; 4.212)	0.417
Dominant	T/C + T/T	1.555 (0.584; 4.135)	0.377	96.003
Recessive	T/T	1.385 (0.259; 7.414)	0.704	96.648
Overdominant	T/C	1.387 (0.528; 3.639)	0.507	96.350
Additive	—	0.717 (0.335; 1.533)	0.391	96.050
≥65
Codominant	T/T	0.077 (0.006; 1.023)	0.052	44.437
	T/C	0.154 (0.016; 1.471)	0.104
Dominant	T/C + T/T	0.128 (0.014; 1.152)	0.067	42.960
Recessive	T/T	0.280 (0.046; 1.705)	0.167	45.938
Overdominant	T/C	0.500 (0.115; 2.175)	0.355	46.931
Additive	—	3.422 (1.052; 11.130)	0.041	42.961