Evaluation of HLA-G 14 bp Ins/Del and +3142G>C Polymorphism with Susceptibility and Early Disease Activity in Rheumatoid Arthritis

Table 2

Interaction of 14 bp ins/del and +3142G>C polymorphism of HLA-G gene on rheumatoid arthritis (RA) risk.

14 bp ins/del	+3142G>C	RA cases; (%)	Controls; (%)	OR (95% CI)
Ins/ins	GG	27 (13.9)	27 (17.1)	1.00	—	—
Ins/del	GG	84 (43.3)	56 (35.4)	1.50 (0.79–2.82)	0.257	1.000
Del/del	GG	24 (12.4)	6 (3.8)	4.00 (1.41–11.34)	0.010	0.039
Ins/del	GC	34 (17.5)	35 (22.2)	0.97 (0.48–1.98)	0.890	1.000
Del/del	GC	10 (5.2)	14 (8.9)	0.71 (0.27–1.89)	0.624	0.992
Ins/ins	GC	8 (4.1)	7 (4.4)	1.14 (0.36–3.60)	0.922	1.000
Del/del	CC	1 (0.5)	7 (4.4)	0.14 (0.02–1.24)	0.063	0.240
Ins/del	CC	5 (2.6)	6 (3.8)	0.83 (0.23–3.06)	0.927	1.000
Ins/ins	CC	1 (0.5)	0 (0.0)	—	—	—

: Bonferroni-corrected .