Research Article

Evaluation of HLA-G 14 bp Ins/Del and +3142G>C Polymorphism with Susceptibility and Early Disease Activity in Rheumatoid Arthritis

Table 5

Association of HLA-G polymorphism in remitting and nonremitting RA patients.

Genotypes Remitting patients
(%)
Nonremitting patients
(%)
OR (95% CI)

14-bp ins/del
Genotype
 Ins/ins1 (50.0)1 (50.0)1.00
 Ins/del10 (43.5)13 (56.5)0.76 (0.04–13.88)0.897
 Del/del4 (80.0)1 (20.0)4.00 (0.12–137.10)0.912

Allele
 Ins12 (40.0)15 (50.0)1.00
 Del18 (60.0)15 (50.0)1.50 (0.54–4.17)0.602

+3142G>C
Genotype
 GG11 (45.8)13 (54.2)1.00
 CG4 (66.7)2 (33.3)2.36 (0.36–15.46)0.651
 CC0 (0.0)0 (0.0)

Allele
 G26 (63.4)28 (65.1)1.00
 C15 (36.6)15 (34.9)0.90 (0.38–2.14)0.826