The Role of Gut Microbiome Perturbation in Fatigue Induced by Repeated Stress from Chemoradiotherapy: A Proof of Concept Study

Table 3

Medians for alpha diversity indexes before (n = 29), at the middle (n = 26), and at the end (n = 22) of CRT.

Index	Before	Middle	End
	Median	Median	Median
Observed
OTUS	190	176	134
Shannon	6.11	5.90	5.58
Faith	21.14	18.70	14.52
Pielou	0.82	0.80	0.81

The differences in number of samples at each time point were due to either missing stool specimen or antibiotics or probiotic use at time of collection.