Comparative Evaluation of the Reticulocyte Hemoglobin Content Assay When Screening for Iron Deficiency in Elderly Anemic Patients

Table 2

Test characteristics based on optimal Cut-off Values for IDA Screening Determined by ROC Curve Analysis. Abbreviations: CHr, Reticulocyte Hemoglobin Content; MCH, Mean Corpuscular Hemoglobin; TSAT, Transferrin Saturation; sTfR, Soluble Transferrin Receptor; TfR-F Index, sTfR/log Ferritin; IDA, Iron Deficiency Anemia; ROC, Receiver Operation Characteristics.

Variable	Sensitivity (%)	Specificity (%)	Cut-off	ROC area
CHr (pg)	93	69	30.5	0.84
MCH (pg)	93	86	28.5	0.91
TSAT (%)	93	57	12	0.84
sTfR (mg/L)	86	89	2.0	0.92
Ferritin (𝜇g/L)	87	95	30	0.92
TfR-F Index	92	94	1.49	0.97