Research Article

Foetal Haemoglobin, Erythrocytes Containing Foetal Haemoglobin, and Hematological Features in Congolese Patients with Sickle Cell Anaemia

Table 2

Comparison of hematological parameters in SCA patients from different African studies.

CountriesNbMean ageHb (g/dL)PCV (%)RBC (T/L)MCV (fl)MCH (pg)MCHC (g/dL)HbF (%)Ref erences

Tanzania1210.76.4224.72.27108.828.8268.6[14]
Kenya2510.97.85262.54102.430.930.27.5[14]
Angola49.37.3020.72.7088.330.535.32[14]
Nigeria2499.77.53282.7610326.826.89.2[14]
Nigeria947.4263.67.2 [17]
Nigeria20023.67.523.0ā€”79.328.332.52.1[15]
R Congo1169.46.68.8[16]
DR Congo1158.77.023.22.4795.328.330.37.4Personal communication
DR Congo428.96.220.72.389.626.829.77.2Our data

Most of the African SCA patients have Hb less than 8ā€‰g/L and Hb F less than 10%. Large variations of HbF rate were observed in the same country like Nigeria probably because of the heterogeneous population who were tested. In DR Congo, values were almost s similar.