Review Article

Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies

Table 1

Members of the FA signaling pathway found in different species.

Homo sapiensMus musculusDanio rerioDrosophila melanogasterCaenorhabditis elegansArchaeaSaccharomyces cerevisiae

FANCAFancafanca
FANCBFancbfancb
FANCCFanccfancc
FANCD1/BRCA2Fancd1fancd1brca2brc-2
FANCD2Fancd2fancd2fancd2fcd-2
FANCEFancefance
FANCFFancffancf
FANCGFancgfancg
FANCIFancifancifnci-1
FANCJ/BACH1/BRIP1Fancjfancjdog-1
FANCL/PHF9/POGFanclfanclfancl
FANCMFancmfancmfancmfncm-1hefMPH1
FANCN/PALB2Palb2palb2
FANCO/Rad51CRad51rad51C
FANCP/SLX4/BTBD12Slx4mus312him-18

References[10][11][12ā€“14][12, 13, 15][16][16]