Fanconi Anemia Proteins and Their Interacting Partners: A Molecular Puzzle

Table 1

List of FA protein partners.

Functional class	Specific function	Protein name	Interacts with	References
Transcription	Transcriptional repressor	FAZF	FANCC	[112, 147]
		HES1	FANCA, F, G, L	[44]
	Stress-induced chaperone	Hsp70	FANCC	[112, 140]
		GRP94	FANCC	[60, 112]
	Chromatin modifier	BRG1	FANCA	[112, 154]
Cell cycle	Serine/threonine kinase	cdc2	FANCC	[86, 112]
Cell signaling	Cytokine response	STAT1	FANCC	[133]
		IKK2	FANCA	[79, 82, 112]
	Secondary modification	Akt kinase	FANCA	[79, 112]
Oxidative metabolism	Electron transfer	RED	FANCC	[112, 114]
	Cytosolic Detoxifying enzyme	GSTP1	FANCC	[112, 113]
	Metabolism of xenobiotics	CYP2E1	FANCG	[112, 115]
	Antioxidant enzyme	PRDX3	FANCG	[68]
Transporter	Intracellular trafficking	SNX5	FANCA	[66, 112]