| (a) Association between eGFR category, ESA use, and transfusion status in hospital LOS |
| | | Unadjusted data | Adjusted data* | | | Relative change (95% CI) | | Relative change (95% CI) | |
| | eGFR range | | | | | | Dialysis | 16.6% (−0.03–40.0%) | 0.095 | 0.06% (−0.12–28.7%) | 0.537 | | <30 | 0.02% (−0.07–12.9%) | 0.620 | 0.02% (−0.12–19.7%) | 0.763 | | 30–59 | −0.01% (−0.08–6.8%) | 0.837 | 0.01% (−0.10–14.5%) | 0.819 | | ≥60 | — | — | — | — | | ESA use | 94.9% (74.9–117.1%) | <0.001 | 28.4% (14.6–43.9%) | <0.001 | | PRBC | −0.11% (−0.20–0.01%) | 0.028 | 0.01% (−0.07–8.9%) | 0.914 |
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*
Adjusted for mortality, age, race, sex, ICU LOS, anemia status, ESA use, transfusion status, mechanical ventilation status, CPAP status, vasopressor use, severity of illness, and presence of, following comorbid conditions, GI bleed, sepsis, acute renal failure, and neurologic injury.
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| (b) Association between eGFR category, ESA use, and transfusion status in ICU LOS |
| | | Unadjusted data | Adjusted data* | | | Relative change (95% CI) | P | Relative change (95% CI) | P |
| | eGFR range | | | | | | Dialysis | 0.06% (−0.22–13.3%) | 0.505 | 0.04% (−0.17–29.0%) | 0.757 | | <30 | 0.03% (−0.06–12.5%) | 0.535 | 17.9% (0.07–29.7%) | 0.001 | | 30–59 | 0.04% (−0.04–12.5%) | 0.379 | 16.8% (0.05–30.1%) | 0.005 | | ≥60 | — | — | — | — | | ESA use | 96.3% (71.7–124.4%) | <0.001 | 0.04% (−0.07–15.8%) | 0.479 | | PRBC | 0.16% (−0.26–0.04%) | 0.008 | 0.01% (−0.08–10.9%) | 0.855 |
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*
Adjusted for mortality, age, race, sex, ICU LOS, ESA use, transfusion status, mechanical ventilation status, CPAP status, vasopressor use, severity of illness, and presence of, following comorbid conditions, GI bleed, sepsis, acute renal failure, and neurologic injury.
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