Chelation Therapy with Oral Solution of Deferiprone in Transfusional Iron-Overloaded Children with Hemoglobinopathies

Table 2

Hematological and biochemical markers during treatment with oral solution of deferiprone (Ferriprox 100 mg/mL) in nine children (4 under 6 years, 5 above 6 years) with transfusion dependent hemoglobinopathies.

Parameters	Total		<6 years		>6 years
	Initial	Final	Initial	Final	Initial	Final
White blood cells (×10^9/L)	6.5±0.6	6.7±1.2	5.9±1.4	6.3±2.1	6.8±1.3	6.1±0.8
Hemoglobin (g/L)	95±8	94±6	89±9	93±7	97±1.1	93±7
Platelets (×10^9/L)	178.2±56.9	165.4±58.4	182.4±91.8	175.5±56.2	174.8±66.3	180.7±95.7
AST (U/L)	43.5±15.4	39.2±14.6	42.3±17.5	39.7±20.5	38.9±13.8	41.8±13.7
ALT (U/L)	53.1±16.5	51.4±13.7	50.8±12.9	49.8±19.1	54.2±17.2	51.8±15.4
Creatinine (μmol/L)	65±12	72±15	68±12	70±11	68±19	72±16
Ferritin (μg/L)	2440±1275	1420±730^∗	2250±880	1575±810^∗	2950±1550	1390±985^∗

Values presented as mean ± SE; ^∗𝑃<0.05.