Direct Comparison of the Safety and Efficacy of Ferric Carboxymaltose versus Iron Dextran in Patients with Iron Deficiency Anemia
Table 6
Changes in hemoglobin, ferritin, and TSAT values.
FCM ()
DEX ()
Hemoglobin (g/dL)
Baseline
Mean (SD)
9.6 (1.18)
9.4 (1.31)
Median
9.9
9.8
Highest value
Mean (SD)
12.4 (1.26)
11.9 (1.47)
Median
12.5
11.8
Change to highest value
Mean (SD)
2.8 (1.44)
2.4 (1.71)
Median
2.7
2.7
value (within group)a
0.001†
0.001
value (versus FCM)b
0.200
Ferritin (ng/mL)
Baseline
Mean (SD)
11.6 (19.29)
21.2 (44.62)
Median
6.2
5.9
Highest value
Mean (SD)
554.7 (287.84)
340.8 (245.46)
Median
503.5
278.8
Change to highest value
Mean (SD)
543.2 (280.06)
319.7 (239.96)
Median
491.9
268.9
value (within group)a
0.001†
0.001†
value (versus FCM)b
0.001†
TSAT (%)
Baseline
Mean (SD)
10.2 (10.27)
9.6 (8.89)
Median
7.0
5.5
Highest value
Mean (SD)
39.8 (15.45)
47.7 (20.73)
Median
39.0
48.0
Change to highest value
Mean (SD)
29.6 (18.02)
38.1 (22.06)
Median
28.0
39.5
value (within group)a
0.001†
0.001†
value (versus FCM)b
0.012*
SD: standard deviation.
a value from the paired -test for the within group change from baseline.
b value from 1-way ANOVA.
*Statistically significant at . †Statistically significant at .
