Clinical Study

The Impact of an Algorithm-Guided Management of Preoperative Anemia in Perioperative Hemoglobin Level and Transfusion of Major Orthopedic Surgery Patients

Figure 3

Thomas-plot. Functional ID was defined as a  pg. The cut-off for sTfR/log ferritin ratio depended on the CRP value and was 1.5 for simple ID (  mg/L) and 0.8 for ID combined with acute phase reaction (  mg/L). Quadrant 1 indicated ACD without functional ID, quadrant 2 latent ID, quadrant 3 manifest ID, and quadrant 4 a combined state of functional ID and ACD. CHr: reticulocyte hemoglobin content, sTfR: soluble transferrin receptor, CRP: C-reactive protein, ACD: anemia of chronic disease, ID: iron deficiency.
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