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Anemia
Volume 2014, Article ID 312302, 6 pages
http://dx.doi.org/10.1155/2014/312302
Research Article

Cormic Index Profile of Children with Sickle Cell Anaemia in Lagos, Nigeria

Department of Paediatrics, Lagos State University Teaching Hospital, P.O. Box 11950, Ikeja, Lagos 100001, Nigeria

Received 27 January 2014; Revised 18 March 2014; Accepted 19 March 2014; Published 17 April 2014

Academic Editor: Aurelio Maggio

Copyright © 2014 Samuel Olufemi Akodu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Sickle cell disorders are known to have a negative effect on linear growth. This could potentially affect proportional growth and, hence, Cormic Index. Objective. To determine the Cormic Index in the sickle cell anaemia population in Lagos. Methodology. A consecutive sample of 100 children with haemoglobin genotype SS, aged eight months to 15 years, and 100 age and sex matched controls (haemoglobin genotype AA) was studied. Sitting height (upper segment) and full length or height were measured. Sitting height was then expressed as a percentage of full length/height (Cormic Index). Results. The mean Cormic Index decreased with age among primary subjects (SS) and AA controls. The overall mean Cormic Index among primary subjects was comparable to that of controls ( % versus %; % versus %) in boys and girls, respectively. In comparison with AA controls, female children with sickle cell anaemia who were older than 10 years had a significantly lower mean Cormic Index. Conclusion. There was a significant negative relationship between Cormic Index and height in subjects and controls irrespective of gender. Similarly, a significant negative correlation existed between age, sitting height, subischial leg length, weight, and Cormic Index in both subjects and controls.