Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations
Table 4
Average calculated iron deficit dose in clinical Studies 6 and 7.
Study
Patient population
Treatment group
Calculated mean iron deficit based on the modified Ganzoni formula (mg)
Standard deviation
Number of patients
Total mean
Study 6
IDA of various etiologies
Cohort 1 (A): 1500 mg IV iron Cohort 1 (B): oral iron Cohort 2 (C): 1500 mg IV iron Cohort 2 (D): IV SoC
1340 1344 1600 1703
356 360 446 482
246 253 252 245
1496 mg
Study 7 (REPAIR-IDA)
NDD-CKD
1500 mg IV iron 1000 mg IV iron
1355 1349
401 403
1275 1285
1352 mg
Overall mean
1392
NC
3556
IDA = iron deficiency anemia; NDD-CKD = non-dialysis-dependent chronic kidney disease; SoC = standard of care; NC = not calculated.
Data on file, Luitpold Pharmaceuticals, Inc.
