Hyaluronan Does Not Affect Bupivacaine’s Inhibitory Action on Voltage-Gated Potassium Channel Activities in Bovine Articular Chondrocytes
Figure 1
Representative whole cell patch clamp recordings showing outward currents elicited by step depolarization from −90 mV to 150 mV with 5 mV increments and holding for 200 ms. Bovine articular chondrocytes were treated with PBS (a), 7.5 mg/mL hyaluronan (b), 0.25% bupivacaine (c), and a mixture of 7.5 mg/mL hyaluronan and 0.25% bupivacaine (d).
