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Advances in Orthopedics
Volume 2012 (2012), Article ID 361534, 6 pages
http://dx.doi.org/10.1155/2012/361534
Research Article

Hyaluronan Does Not Affect Bupivacaine’s Inhibitory Action on Voltage-Gated Potassium Channel Activities in Bovine Articular Chondrocytes

1Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, LA 70112, USA
2Department of Orthopaedic Surgery and Tulane Institute of Sports Medicine, Tulane University School of Medicine, New Orleans, LA, USA
3Tulane Cancer Center, Louisiana Cancer Research Consortium, Tulane Center for Aging, Tulane Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA

Received 21 January 2012; Accepted 24 February 2012

Academic Editor: Masato Takao

Copyright © 2012 William Hester et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. C. Allen, M. A. S. Amand, A. C. P. Lui, D. H. Johnson, and M. P. Lindsay, “Postarthroscopy analgesia with intraarticular bupivacaine/morphine: a randomized clinical trial,” Anesthesiology, vol. 79, no. 3, pp. 475–480, 1993. View at Google Scholar · View at Scopus
  2. A. Scholz, “Mechanisms of (local) anaesthetics on voltage-gated sodium and other ion channels,” British Journal of Anaesthesia, vol. 89, no. 1, pp. 52–61, 2002. View at Publisher · View at Google Scholar · View at Scopus
  3. K. R. Courtney and J. J. Kendig, “Bupivacaine is an effective potassium channel blocker in heart,” Biochimica et Biophysica Acta—Biomembranes, vol. 939, no. 1, pp. 163–166, 1988. View at Google Scholar · View at Scopus
  4. X. Li, A. Shah, P. Franklin, R. Merolli, J. Bradley, and B. Busconi, “Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid (Orthovisc) treatment: a case series and review of the literature,” Journal of Orthopaedic Surgery and Research, vol. 3, no. 1, article no. 43, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Gomis, M. Pawlak, E. A. Balazs, R. F. Schmidt, and C. Belmonte, “Effects of different molecular weight elastoviscous hyaluronan solutions on articular nociceptive afferents,” Arthritis and Rheumatism, vol. 50, no. 1, pp. 314–326, 2004. View at Publisher · View at Google Scholar · View at Scopus
  6. C. R. Chu, N. J. Izzo, C. H. Coyle, N. E. Papas, and A. Logar, “The in vitro effects of bupivacaine on articular chondrocytes,” Journal of Bone and Joint Surgery, vol. 90, no. 6, pp. 814–820, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. A. H. Gomoll, R. W. Kang, J. M. Williams, B. R. Bach, and B. J. Cole, “Chondrolysis after continuous intra-articular bupivacaine infusion: an experimental model investigating chondrotoxicity in the rabbit shoulder,” Arthroscopy, vol. 22, no. 8, pp. 813–819, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. B. Farkas, K. Kvell, T. Czömpöly, T. Illés, and T. Bárdos, “Increased chondrocyte death after steroid and local anesthetic combination,” Clinical Orthopaedics and Related Research, vol. 468, no. 11, pp. 3112–3120, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. S. T. Webb and S. Ghosh, “Intra-articular bupivacaine: potentially chondrotoxic?” British Journal of Anaesthesia, vol. 102, no. 4, pp. 439–441, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. B. T. Busfield and D. M. Romero, “Pain pump use after shoulder arthroscopy as a cause of glenohumeral chondrolysis,” Arthroscopy, vol. 25, no. 6, pp. 647–652, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Liu, Q.-S. Zhang, W. Hester, M. J. O’Brien, F. H. Savoie, and Z. You, “Hyaluronan protects bovine articular chondrocytes against cell death induced by Bupivacaine under supraphysiologic temperatures,” The American Journal of Sports Medicine. In press.
  12. J. Yang, J. P. Nemargut, and G.-Y. Wang, “The roles of ionotropic glutamate receptors along the On and Off signaling pathways in the light-adapted mouse retina,” Brain Research, vol. 1390, pp. 70–79, 2011. View at Publisher · View at Google Scholar
  13. D. Goldoni, Y. Zhao, B. D. Green, B. J. McDermott, and A. Collins, “Inward rectifier potassium channels in the HL-1 cardiomyocyte-derived cell line,” Journal of Cellular Physiology, vol. 225, no. 3, pp. 751–756, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Komai and T. S. McDowell, “Local anesthetic inhibition of voltage-activated potassium currents in rat dorsal root ganglion neurons,” Anesthesiology, vol. 94, no. 6, pp. 1089–1095, 2001. View at Google Scholar · View at Scopus
  15. A. Olschewski, H. Olschewski, M. E. Bräu, G. Hempelmann, W. Vogel, and B. V. Safronov, “Effect of bupivacaine on ATP-dependent potassium channels in rat cardiomyocytes,” British Journal of Anaesthesia, vol. 82, no. 3, pp. 435–438, 1999. View at Google Scholar · View at Scopus
  16. M. T. Bogatch, D. G. Ferachi, B. Kyle et al., “Is chemical incompatibility responsible for chondrocyte death induced by local anesthetics?” The American Journal of Sports Medicine, vol. 38, no. 3, pp. 520–526, 2010. View at Google Scholar · View at Scopus
  17. H. G. Hassan, B. Akerman, and H. Renck, “Effects of adjuvants to local anaesthetics on their duration. III. Experimental studies of hyaluronic acid,” Acta Anaesthesiologica Scandinavica, vol. 29, no. 4, pp. 384–388, 1985. View at Google Scholar
  18. I. Mahé, S. Mouly, I. Jarrin et al., “Efficacy and safety of three ophthalmic inserts for topical anaesthesia of the cornea. An exploratory comparative dose-ranging, double-blind, randomized trial in healthy volunteers,” British Journal of Clinical Pharmacology, vol. 59, no. 2, pp. 220–226, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. V. Grishko, M. Xu, G. Wilson, and A. W. Pearsall, “Apoptosis and mitochondrial dysfunction in human chondrocytes following exposure to lidocaine, bupivacaine, and ropivacaine,” Journal of Bone and Joint Surgery, vol. 92, no. 3, pp. 609–618, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. V. Grishko, M. Xu, R. Ho et al., “Effects of hyaluronic acid on mitochondrial function and mitochondria-driven apoptosis following oxidative stress in human chondrocytes,” Journal of Biological Chemistry, vol. 284, no. 14, pp. 9132–9139, 2009. View at Publisher · View at Google Scholar · View at Scopus