Two-Stage Revision TKA Is Associated with High Complication and Failure Rates

Table 6

Failure and mortality rates reported in prior studies for two-stage revision TKA.

Reference (authors)	Year	Failure defined	Number of knees	Mean follow-up (months)	Failure rate (%)	Overall mortality rate (%)	90-day mortality rate (%)
Current study	2013	Persistent infection	66	40 (0–113)	24	23 (15/66)	1.5 (1/66)
Cai et al. [19]	2012	Reinfection	23	43 (24–60)	9	NR	NR
Kubista et al. [18]	2012	Reinfection	368	43 (1–93.6)	16	NR	NR
Mahmud et al. [20]	2012	SSI	253	12 (12–204)	13	NR	NR
Radoicic et al. [9]	2012	SSI	21	35–47	24	NR	NR
Tigani et al. [17]	2013	SSI	38	65 (24–139)	23.6	NR	NR
Gooding et al. [21]	2011	Reinfection	115	108 (60–144)	12	30 (32/115)	NR
Sherrell et al.^* [16]	2011	SSI	83	50 (1–151)	34	14 (12/83)	NR
Mortazavi et al. [14]	2011	SSI	117	41 (24–113)	28	NR	NR
Macheras et al. [22]	2011	Reinfection	34	145 (120–168)	9	NR	NR
Kurd et al. [23]	2010	SSI	96	35 (24–90)	27	NR	NR
Kosters et al. [24]	2009	Reinfection	6	25 (2–61)	0	NR	NR
Hofmann et al. [25]	2005	Reinfection	50	74 (24–150)	12	22 (11/50)	NR
Average					17.3	22

SSI = subsequent surgery for reinfection; NR = not reported.
^*Two-Stage after failed I&D.