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Advances in Orthopedics

Volume 2014, Article ID 986285, 9 pages

http://dx.doi.org/10.1155/2014/986285
Review Article

Is End-Stage Ankle Arthrosis Best Managed with Total Ankle Replacement or Arthrodesis? A Systematic Review

1University Hospitals Coventry & Warwickshire, Clifford Bridge Road, Coventry CV2 2DX, UK

2Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK

Received 24 May 2014; Accepted 12 August 2014; Published 21 August 2014

Academic Editor: Allen L. Carl

Copyright © 2014 Robert W. Jordan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. End-stage ankle osteoarthritis is a debilitating condition. Traditionally, ankle arthrodesis (AA) has been the surgical intervention of choice but the emergence of total ankle replacement (TAR) has challenged this concept. This systematic review aims to address whether TAR or AA is optimal in terms of functional outcomes. Methods. We conducted a systematic review according to PRISMA checklist using the online databases Medline and EMBASE after January 1, 2005. Participants must be skeletally mature and suffering from ankle arthrosis of any cause. The intervention had to be an uncemented TAR comprising two or three modular components. The comparative group could include any type of ankle arthrodesis, either open or arthroscopic, using any implant for fixation. The study must have reported at least one functional outcome measure. Results. Of the four studies included, two reported some significant improvement in functional outcome in favour of TAR. The complication rate was higher in the TAR group. However, the quality of studies reviewed was poor and the methodological weaknesses limited any definitive conclusions being drawn. Conclusion. The available literature is insufficient to conclude which treatment is superior. Further research is indicated and should be in the form of an adequately powered randomised controlled trial.

1. Introduction

End-stage ankle osteoarthritis is a debilitating condition that results in functional limitations and a poor quality of life [1]. The incidence of symptomatic osteoarthritis of the ankle has been estimated to be 47.7/100,000 in the United Kingdom [2]. More than 70% is related to posttraumatic osteoarthritis [1, 3] with the majority of the remainder being primary arthritis, inflammatory arthritis, or secondary to osteonecrosis. Mild to moderate ankle arthritis can often be managed with ankle foot orthoses and a rocker-bottom shoe [4]. When surgical intervention is indicated, ankle arthrodesis (AA) has traditionally been used. However, the development of total ankle replacement (TAR) has challenged arthrodesis as the treatment of choice for ankle arthrosis [57].

AA has been shown to give good results in multiple papers [810]. Various techniques have been used which include cannulated screws, plate fixation, retrograde nail, and external fixation. The main drawback of the procedure is the high rate of later arthrosis in adjacent joints, reported between 10 and 60% [1113]. This results in a subsequent subtalar fusion rate at 5 years of 2.8% which is higher than the 0.7% after TAR [14]. Additional complications associated with AA include wound infection (3–25%), nonunion (10–20%), and malalignment [15, 16].

TAR is still evolving [17] but has the potential advantage to preserve range of motion, restore gait, and, thus, protect adjacent articulations [18]. The results from first generation ankle prosthesis were disappointing with stiffness, wound complications, loosening, malalignment, impingement, and instability cited as causes of failure [7, 1921]. Newer prosthesis is uncemented, comprises two or three modular components, and has improved outcomes. A recent systematic review reported 89% survival of 7942 TARs at 10 years and an improvement in American Orthopaedic Foot and Ankle Society score (AOFAS) from 40 to 80 at a mean of 8.2 years of follow-up [22]. However, a further review from Gougoulias et al. of 1105 total ankle arthroplasties reported a 10% failure rate at 5 years with residual pain in 27%–60% of cases [23].

Haddad et al. performed a systematic review of the literature up until 2005 comparing outcomes following second generation TAR and AA. However, the majority of the 49 studies reviewed were single centre case series and none directly compared the two treatments. They concluded that both techniques gave comparable intermediate and long-term outcomes, reporting good or excellent outcomes in 68.5% of TAR and 67% of AA patients and mean AOFAS scores of 78.2 following TAR and 75.6 following AA. However, variability of reporting outcomes and lack of controlled studies restricted direct comparisons of the two groups [24]. The aim of this paper is to perform an up-to-date systematic review of the literature including only comparative studies addressing whether TAR or AA is optimal in the treatment of end-stage ankle arthrosis in terms of functional outcomes.

2. Methods

We conducted a systematic review of the literature using the online databases Medline and EMBASE. The review was performed and reported according to the PRISMA checklist. The search strategy used for the Medline search is shown in Table 1 and this was modified for searching EMBASE. The searches were carried out on January 15, 2014, and limited to papers available in English. The search was limited to papers published after January 1, 2005, as the previous systematic review published in 2007 included papers prior to this date [24].

tab1
Table 1: Search strategy for Medline.

Inclusion criteria were applied. Participants must be skeletally mature and suffering from ankle arthrosis of any cause deemed severe enough to warrant either TAR or AA by the treating surgeon. The intervention had to be an uncemented TAR comprising two or three modular components. The comparative group could include any type of ankle arthrodesis, either open or arthroscopic, using any implant for fixation. The study must have reported at least one functional outcome measure. Studies were excluded if no comparative group was analysed or if the study participants were divided into more than two groups. In addition, only primary research was considered for review with any abstracts, comments, review articles, and technique articles excluded. Eligibility of studies was assessed independently by two authors (R.J. and G.C.) who also appraised the included studies against the STROBE statement [25]. If there was any disagreement between the authors in assigning a score to each paper appraised, a third independent reviewer (A.C.) made the final decision.

3. Results

The Medline search revealed 88 and the EMBASE search 126 results. Figure 1 shows a flow diagram of the review process including the reasons for exclusion at different stages of the process. Concise details of the included studies are given in Table 2 and the appraisal against STROBE statement [25] is given in Table 3. The reasons for exclusion of the 10 articles at full paper review stage are given in Table 4.

tab2
Table 2: Summary of the included studies.
tab3
Table 3: Assessment of papers according to STROBE statement [24].
tab4
Table 4: Reason for exclusion of studies after full paper review.
986285.fig.001
Figure 1: Flow diagram of review process.

Of the four studies included, three were level III retrospective comparative studies and the other was a level II prospective comparative study. The optimal study design when comparing two treatment modalities is a randomised controlled trial (RCT) as this allows for minimisation of bias. The main limitation that is common to all four studies reviewed is the lack of randomisation; this risks selection bias with the uneven allocation of confounding factors between the groups. In addition, as none of the studies reviewed defined a primary outcome measure or included a power calculation, uncertainty is present as to whether any of the studies was sufficiently powered to show a significant difference in any recorded outcome measure.

Schuh et al., 2012. Schuh et al. [26] performed a retrospective review of 63 patients that underwent either TAR, using a HINTEGRA prosthesis (Newdeal SA, Lyon, France), or AA, using 3 cannulated screws. No significant difference was found between the two groups in terms of activity level, participation in sport, or American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score. The surgery was performed by a single, fellowship trained surgeon between 1998 and 2006. Of the 63 patients assessed, only 41 were included for analysis. The 16% loss to follow-up forms a high proportion and the majority (70%) of these were in the AA group. The reason these patients refused follow-up is not known and their exclusion may have skewed results. Minimal details of the inclusion criteria are stated and whether patients with arthrosis of any cause were included is not clear. Clarity is required to decide whether results are applicable to other populations. In addition, no mention is given as to whether assessments were performed by an independent observer or the postoperative physiotherapy regimen was consistent between the two groups.

Esparragoza et al., 2011. Esparragoza et al. [27] performed a prospective comparative study of 30 patients. Surgery was performed by a total of 6 senior staff members of whom 3 performed all of the TAR and 3 all of the AA. All patients undergoing TAR had the Ankle Evolution System implant (Biomet, Nimes, France) inserted but arthrodesis was performed by three different techniques. A statistically significant improvement in AOFAS () and SF-36 () in the TAR group was reported at two years. However, the study had a number of limitations including a lack of randomisation and inclusion of only a small number of patients. Although the reported baseline characteristics are similar between the groups, further information on adjacent joint arthrosis would have been beneficial. Those patients undergoing arthrodesis were further divided into three techniques, which introduces heterogeneity amongst this arthrodesis group. Provision of outcomes for each technique would have demonstrated whether all techniques had equal effectiveness but the low number of patients studied precluded this. Again, details regarding the postoperative physiotherapy regime and those responsible for measuring outcomes should have been provided.

Krause et al., 2011. Krause et al. [28] performed a retrospective comparative study of 161 patients. No statistically significant difference in functional outcome was reported between the groups; however, TAR patients had a higher complication rate (). Clear indications for each procedure are set out and details regarding the surgical technique, surgeon experience, postoperative regime, and definitions of terms are given. Due to strict inclusion and exclusion criteria, only 31% of patients were deemed eligible to participate limiting the external validity of results. The authors excluded cases where a failed arthrodesis was converted to a TAR but included cases where a failed TAR was converted to AA. Conversion procedures are likely to be more complex and so, prone to worse results; the inclusion of failed TAR but not failed AA potentially increases the complexity of cases in the AA group and this may have impacted outcomes. The ankle replacement used as the intervention could be one of four prostheses depending on surgeon preference: the Agility ankle system (Depuy, Warsaw, IN, USA), the Mobility ankle system (Depuy, Warsaw, IN, USA), Scandinavian Total Ankle Replacement (STAR) (Waldmar Link, Hamburg, Germany), and HINTEGRA prosthesis (Newdeal SA, Lyon, France). This is a pragmatic approach but the outcomes of different prostheses may vary and this is not accounted for in the study. Comparison between the two groups is limited by their differences at baseline and complexity of surgery performed. The fusion group was younger, had a lower proportion of rheumatoid arthritis, and had a much higher proportion of low complexity surgery (87% versus 32%); any positive results may result from these differences rather than the type of surgery received.

Saltzman et al., 2010. Saltzman et al. [29] performed a retrospective comparative study of 71 patients undergoing either TAR or AA, using a STAR (Waldmar Link, Hamburg, Germany). A significant improvement in the TAR group in the pain component of Ankle Osteoarthritis Scale (AOS) () and the mental component of SF-36 () was reported. Initially, 138 patients were assessed for eligibility but 67 did not satisfy inclusion criteria and this high number questions the external validity of results. Of the 71 included, 11 were lost to follow-up, with slightly more lost in the AA group. Patients undergoing TAR with an alternative prosthesis were excluded; in contrast, those undergoing AA had three different surgical techniques performed. This approach is slightly contradictory as there is an assumption that patients having differing TAR replacements may have varying outcomes but those having various arthrodeses have equal outcomes. A pragmatic approach would be to compare all replacements versus all arthrodeses, or alternatively to compare one replacement against one fusion technique. At the beginning of this section, the importance of randomisation and transparency of treatment allocation was discussed. In the current study, the AA group had a higher number of young patients, males, and those with posttraumatic arthritis. Each of these factors may directly influence outcome and thus any positive results cannot be confidently attributed to the treatment given. Outcome measures have only been recorded postoperatively and the lack of preoperative value limits the value of the results as the degree of improvement following treatment is not known.

4. Discussion

Four studies were identified and reviewed which addressed our research question. Two of the four studies reported statistically significant improvements in functional outcomes following TAR [27, 29]; the other two studies showed no differences between the two groups [26, 28]. However, the methodological flaws present stop definitive conclusions being drawn.

The main limitation in design common to all studies was the lack of randomisation. This risks differences in the study groups being present at the point of treatment allocation which has the potential to affect results. Only one study described the indications for the two procedures [28], using severe deformity or instability, poor ankle motion, no or mild adjacent joint arthritis, and younger age as indications of arthrodesis. Therefore, the arthrodesis group in this study will have had a higher proportion of patients with these factors than the TAR group, which all may have influenced outcomes. The other three studies [26, 27, 29] do not describe the indications used for allocation but it is likely that baseline characteristics also differed in these studies, limiting the ability to directly compare outcomes between the two groups. A further limitation of the systematic review is the use of pragmatic entry criteria for the intervention and comparator groups, with all arthrodesis procedures and any uncemented ankle replacement included. The four studies included used five different uncemented ankle prostheses and four fixation methods for arthrodesis including open and arthroscopic techniques. The inclusion of numerous surgical techniques restricts the generalisability of the results to any specific technique as it is likely that the outcomes following each method differ.

Although at least one functional outcome was measured in each study, the evidence supporting the validity, reliability, and responsiveness of the available measures following foot and ankle surgery is limited [30, 31]. The AOFAS is the most commonly used outcome measure following foot and ankle surgery [30, 31] but it relies on the observer to measure both range of motion and malalignment, risking observer bias. The AOS is patient reported which reduces the risk of observer bias and has been validated in ankle osteoarthritis, but it is not validated in the measurement of outcome following AA or TAR. Therefore, neither of the two functional measures provides an ideal measurement tool and may have contributed to inaccurate recording of outcomes. Future research should utilise an outcome tool that both is patient reported and is validated for use in this postoperative population.

At present, the evidence is insufficient to change clinical practice. Arthrodesis has been the traditional treatment of choice and will continue to be so until the literature definitively demonstrates one modality to be superior to the other. The increased rate of complications reported following TAR further supports this approach [28]. Ideally, future research will be of RCT design so that selection bias is limited and effects measured can be attributed to treatment allocation. The population treated needs to be clearly defined so that results can be applied to the readers’ practice. They should have a patient reported outcome as the defined primary outcome and the study should be adequately powered to show a statistically significant difference between the groups.

5. Conclusion

Although half of the reviewed studies report some functional improvement following total ankle replacement, the lack of high quality evidence limits a definitive conclusion being drawn. Insufficient evidence is available to decide whether total ankle replacement or ankle arthrodesis improves functional outcomes and further research in the form of robust RCTs is indicated.

Conflict of Interests

The authors have no conflict of interests to declare and received no funding during the production of this systematic review.

References

  1. C. L. Saltzman, M. B. Zimmerman, M. O'Rourke, T. D. Brown, J. A. Buckwalter, and R. Johnston, “Impact of comorbidities on the measurement of health in patients with ankle osteoarthritis,” Journal of Bone and Joint Surgery A, vol. 88, no. 11, pp. 2366–2372, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. A. J. Goldberg, A. MacGregor, J. Dawson et al., “The demand incidence of symptomatic ankle osteoarthritis presenting to foot & ankle surgeons in the United Kingdom,” Foot, vol. 22, no. 3, pp. 163–166, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. R. Thomas, T. R. Daniels, and K. Parker, “Gait analysis and functional outcomes following ankle arthrodesis for isolated ankle arthritis,” Journal of Bone and Joint Surgery A, vol. 88, no. 3, pp. 526–535, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. R. L. Martin, G. W. Stewart, and S. F. Conti, “Posttraumatic ankle arthritis: an update on conservative and surgical management,” Journal of Orthopaedic and Sports Physical Therapy, vol. 37, no. 5, pp. 253–259, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. M. T. Pyevich, C. L. Saltzman, J. J. Callaghan, and F. G. Alvine, “Total ankle arthroplasty: a unique design: two to twelve-year follow-up,” Journal of Bone and Joint Surgery A, vol. 80, no. 10, pp. 1410–1420, 1998. View at Google Scholar · View at Scopus
  6. T. Anderson, F. Montgomery, and A. Carlsson, “Uncemented STAR total ankle prostheses: three to eight-year follow-up of fifty-one consecutive ankles,” Journal of Bone and Joint Surgery A, vol. 85, no. 7, pp. 1321–1329, 2003. View at Google Scholar · View at Scopus
  7. H. Kofoed and T. S. Sørensen, “Ankle arthroplasty for rheumatoid arthritis and osteoarthritis,” Journal of Bone and Joint Surgery B, vol. 80, no. 2, pp. 328–332, 1998. View at Publisher · View at Google Scholar · View at Scopus
  8. Y. Chen, T. Huang, H. Shih, K. Hsu, and R. W. Hsu, “Ankle arthrodesis with cross-screw fixation. Good results in 36/40 cases followed 3–7 years,” Acta Orthopaedica Scandinavica, vol. 67, no. 5, pp. 473–479, 1996. View at Google Scholar · View at Scopus
  9. E. S. Holt, S. T. Hansen, K. A. Mayo, and B. J. Sangeorzan, “Ankle arthrodesis using internal screw fixation,” Clinical Orthopaedics and Related Research, vol. 268, pp. 21–28, 1991. View at Google Scholar · View at Scopus
  10. R. H. Thomas and T. R. Daniels, “Ankle arthritis,” Journal of Bone and Joint Surgery A, vol. 85, no. 5, pp. 923–936, 2003. View at Google Scholar · View at Scopus
  11. L. M. Coester, C. L. Saltzman, J. Leupold, and W. Pontarelli, “Long-term results following ankle arthrodesis for post-traumatic arthritis,” Journal of Bone and Joint Surgery A, vol. 83, no. 2, pp. 219–228, 2001. View at Google Scholar · View at Scopus
  12. S. Fuchs, C. Sandmann, A. Skwara, and C. Chylarecki, “Quality of life 20 years arthrodesis of the ankle,” Journal of Bone and Joint Surgery B, vol. 85, no. 7, pp. 994–998, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. B. F. Morrey and G. P. Wideman Jr., “Complications and long-term results of ankle arthrodeses following trauma,” Journal of Bone and Joint Surgery A, vol. 62, no. 5, pp. 777–784, 1980. View at Google Scholar · View at Scopus
  14. N. F. SooHoo, D. S. Zingmond, and C. Y. Ko, “Comparison of reoperation rates following ankle arthrodesis and total ankle arthroplasty,” Journal of Bone and Joint Surgery - Series A, vol. 89, no. 10, pp. 2143–2149, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Bauer and L. Kinzl, “Arthrodesis of the ankle joint,” Orthopade, vol. 25, no. 2, pp. 158–165, 1996. View at Google Scholar · View at Scopus
  16. P. S. Cooper, “Complications of ankle and tibiotalocalcaneal arthrodesis,” Clinical Orthopaedics and Related Research, no. 391, pp. 33–44, 2001. View at Google Scholar · View at Scopus
  17. P. Culpan, V. Le Strat, P. Piriou, and T. Judet, “Arthrodesis after failed total ankle replacement,” Journal of Bone and Joint Surgery - Series B, vol. 89, no. 9, pp. 1178–1183, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Piriou, P. Culpan, M. Mullins, J. N. Cardon, D. Pozzi, and T. Judet, “Ankle replacement versus arthrodesis: a comparative gait analysis study,” Foot and Ankle International, vol. 29, no. 1, pp. 3–9, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. S. E. Newton, “Total ankle arthroplasty. Clinical study of fifty cases,” Journal of Bone and Joint Surgery A, vol. 64, no. 1, pp. 104–111, 1982. View at Google Scholar · View at Scopus
  20. B. G. Bolton-Maggs, R. A. Sudlow, and M. A. R. Freeman, “Total ankle arthroplasty: a long-term review of the London hospital experience,” Journal of Bone and Joint Surgery B, vol. 67, no. 5, pp. 785–790, 1985. View at Google Scholar · View at Scopus
  21. H. B. Kitaoka, G. L. Patzer, D. M. Ilstrup, and S. L. Wallrichs, “Survivorship analysis of the Mayo total ankle arthroplasty,” Journal of Bone and Joint Surgery A, vol. 76, no. 7, pp. 974–979, 1994. View at Google Scholar · View at Scopus
  22. R. Zaidi, S. Cro, K. Gurusamy et al., “The outcome of total ankle replacement: a systematic review and meta-analysis,” The Bone & Joint Journal, vol. 95, no. 11, pp. 1500–1507, 2013. View at Google Scholar
  23. N. Gougoulias, A. Khanna, and N. Maffulli, “How successful are current ankle replacements?: a systematic review of the literature,” Clinical Orthopaedics and Related Research, vol. 468, no. 1, pp. 199–208, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. S. L. Haddad, J. C. Coetzee, R. Estok, K. Fahrbach, D. Banel, and L. Nalysnyk, “Intermediate and long-term outcomes of total ankle arthroplasty and ankle arthrodesis: a systematic review of the literature,” Journal of Bone and Joint Surgery A, vol. 89, no. 9, pp. 1899–1905, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. STROBE statement, 2013, http://www.strobe-statement.org/fileadmin/Strobe/uploads/checklists/STROBE_checklist_v4_combined.pdf.
  26. R. Schuh, J. Hofstaetter, M. Krismer, R. Bevoni, R. Windhager, and H. Trnka, “Total ankle arthroplasty versus ankle arthrodesis. Comparison of sports, recreational activities and functional outcome,” International Orthopaedics, vol. 36, no. 6, pp. 1207–1214, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. L. Esparragoza, C. Vidal, and J. Vaquero, “Comparative study of the quality of life between arthrodesis and total arthroplasty substitution of the ankle,” Journal of Foot and Ankle Surgery, vol. 50, no. 4, pp. 383–387, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. F. G. Krause, M. Windolf, B. Bora, M. J. Penner, K. J. Wing, and A. S. E. Younger, “Impact of complications in total ankle replacement and ankle arthrodesis analyzed with a validated outcome measurement,” Journal of Bone and Joint Surgery A, vol. 93, no. 9, pp. 830–839, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. C. L. Saltzman, R. G. Kadoko, and J. S. Suh, “Treatment of isolated ankle osteoarthritis with arthrodesis or the total ankle replacement: a comparison of early outcomes,” Clinics in Orthopedic Surgery, vol. 2, no. 1, pp. 1–7, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. F. D. Naal, F. M. Impellizzeri, and P. F. Rippstein, “Which are the most frequently used outcome instruments in studies on total ankle arthroplasty?” Clinical Orthopaedics and Related Research, vol. 468, no. 3, pp. 815–826, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. K. J. Hunt and D. Hurwit, “Use of patient-reported outcome measures in foot and ankle research,” Journal of Bone and Joint Surgery A, vol. 95, no. 16, article e118, 9 pages, 2013. View at Google Scholar
  32. “Ankle replacement tops ankle fusion as new gold standard. The procedure has evolved into come in, have surgery, go home the next day,” Duke Medicine Health News, vol. 18, no. 9, 2012.
  33. K. A. Conley, K. Geist, J. N. Shaw, S. A. Labib, and M. A. Johanson, “The effect of goniometric alignment on passive ankle dorsiflexion range of motion among patients following ankle arthrodesis or arthroplasty,” Foot and Ankle Specialist, vol. 5, no. 3, pp. 175–179, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. R. Flavin, S. C. Coleman, S. Tenenbaum, and J. W. Brodsky, “Comparison of gait after total ankle arthroplasty and ankle arthrodesis,” Foot & Ankle International, vol. 34, pp. 1340–1348, 2013. View at Google Scholar
  35. M. E. Hahn, E. S. Wright, A. D. Segal, M. S. Orendurff, W. R. Ledoux, and B. J. Sangeorzan, “Comparative gait analysis of ankle arthrodesis and arthroplasty: initial findings of a prospective study,” Foot and Ankle International, vol. 33, no. 4, pp. 282–289, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. F. G. Krause and T. Schmid, “Ankle arthrodesis versus total ankle replacement. How do I decide?” Foot & Ankle Clinics, vol. 17, no. 4, pp. 529–543, 2012. View at Publisher · View at Google Scholar · View at Scopus
  37. H. Rouhani, X. Crevoisier, J. Favre, and K. Aminian, “Outcome evaluation of ankle osteoarthritis treatments: plantar pressure analysis during relatively long-distance walking,” Clinical Biomechanics, vol. 26, no. 4, pp. 397–404, 2011. View at Publisher · View at Google Scholar · View at Scopus
  38. H. Rouhani, J. Favre, K. Aminian, and X. Crevoisier, “Multi-segment foot kinematics after total ankle replacement and ankle arthrodesis during relatively long-distance gait,” Gait and Posture, vol. 36, no. 3, pp. 561–566, 2012. View at Publisher · View at Google Scholar · View at Scopus
  39. G. P. Slobogean, A. Younger, K. L. Apostle et al., “Preference-based quality of life of end-stage ankle arthritis treated with arthroplasty or arthrodesis,” Foot and Ankle International, vol. 31, no. 7, pp. 563–566, 2010. View at Publisher · View at Google Scholar · View at Scopus